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Tretazicar
go.drugbank.com/drugs/DB04253InvestigationalTretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).
Categories: Heterocyclic Compounds, 1-RingHCV-086
go.drugbank.com/drugs/DB05884ExperimentalHCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.
AMGN-0007
go.drugbank.com/drugs/DB06511ExperimentalRecombinant osteoprotegerin (AMGN-0007) is a recombinant OPG construct developed as a potential therapeutic agent in the treatment of bone disease.
Timapiprant
go.drugbank.com/drugs/DB11900InvestigationalOC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.
Categories: Heterocyclic Compounds, 2-RingAnagliptin
go.drugbank.com/drugs/DB12417InvestigationalAnagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
Categories: Heterocyclic Compounds, 1-RingHSD-016
go.drugbank.com/drugs/DB12419InvestigationalHsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).
Categories: Heterocyclic Compounds, 1-RingMetiamide
go.drugbank.com/drugs/DB08805ExperimentalMetiamide is an H-2 receptor antagonist derived from burimamide. It was an intermediate product on the path to developing cimetidine.
LY-2452473
go.drugbank.com/drugs/DB12573InvestigationalLy2452473 is under investigation for the supportive care of Prostate Cancer. Ly2452473 has been investigated for the treatment of Erectile Dysfunction.
Delpazolid
go.drugbank.com/drugs/DB13077InvestigationalDelpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Categories: Heterocyclic Compounds, 1-RingSynonyms: (R)-3-[3-Fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5(R)-(hydroxymethyl)oxazolidin-2-one, (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-oneTiazofurine
go.drugbank.com/drugs/DB13243ExperimentalTiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase [A174991].
Synonyms: 2-(β-D-ribofuranosyl)-4-thiazolecarboxamide, 2-β-D-ribofuranosyl-4-thiazolecarboxamide