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Displaying results 81 - 90 of 295 in total
  1. Drug

    Lixadesiran

    go.drugbank.com/drugs/DB17295
    Experimental

    Synonyms: Rna, (a-c-a-u-c-a-u-c-a-g-a-c-c-a-g-g-c-a-c-c-a-g-a-c-c), complex with rna (g-g-u-c-u-g-g-u-g-c-c-u-g-g-u-c-u-g-a-u-g-a-u-g-u) (1:1)
  2. Indication

    Tuberous Sclerosis Complex with Renal angiomyolipoma

    go.drugbank.com/conditions/DBCOND0025534
    Drugs: Everolimus
    Synonyms: Tuberous Sclerosis Complex with Renal angiomyolipoma
  3. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0001495
    TargetAchromobacter cycloclastes

    Polypeptides: Copper-containing nitrite reductaseFunction: copper ion binding
  4. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0002802
    TargetAlcaligenes xylosoxydans xylosoxydans

    Polypeptides: Copper-containing nitrite reductaseSynonyms: Dissimilatory copper-containing nitrite reductase
  5. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  6. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  7. Indication

    Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis

    go.drugbank.com/conditions/DBCOND0173486
    Drugs: Pegcetacoplan
    Synonyms: Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis
  8. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0004667
    EnzymePig

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:1457410, PubMed:8144586). Its preferred substrates in vitro are the diamines hi...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1, Amiloride-sensitive amine oxidase [copper-containing]
  9. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0000351
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:12072962, PubMed:19764817, PubMed:239684, PubMed:8144586). Its preferred substr...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1
  10. Target

    Copper transport protein ATOX1

    go.drugbank.com/bio_entities/BE0002833
    TargetCarrierHumans

    Multifunctional copper-sensing protein that operates both as a cytosolic copper chaperone and as a copper-dependent transcription factor. … In the cytosol, transfers copper to the copper-transporting ATPase ATP7A at the trans-Golgi network, which is required for activation of secretory copper enzymes including lysyl oxidase (LOX) and SOD3.

    Polypeptides: Copper transport protein ATOX1