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Clozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[A256713,A256718] However, continued evidence of its effectiveness led to clozapine's eventual reintroduction, although with a reluctance to prescribe it. … [A256708] Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical
Products: CLOZAPIN - CT 25 MG TABL, CLOZAPIN - CT 50 MG TABLGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[L13571] It is therefore not considered to be a disease-modifying drug. … It also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance.
Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETProducts: GALANTAMIN RATIO 24MG RET, GALNORA 24MG HARTKAPS RETPanobinostat
go.drugbank.com/drugs/DB06603ApprovedInvestigationalPanobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent available on the market.
Products: FARYDAK HARD GELATIN CAPSULE 20mg, FARYDAK HARD GELATIN CAPSULE 10mgDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawn(Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942] … It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.
Synonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediolProducts: Honvol Tablets 100mg, Honvol Ampoules 250mgTemazepam
go.drugbank.com/drugs/DB00231ApprovedIn particular, before temazepam saw regular prescription use in civilians it was - and still is - employed by the US military as a sedative-hypnotic medication to be taken by soldiers, pilots, etc. to
Products: TEMAZEP - CT 20MG KAPSELN, REMESTAN MITE 10MGMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: IMPLICOR 50MG/5MG FILM-COATED TABLETS, IMPLICOR 50MG/7.5MG FILM-COATED TABLETSProducts: METODURA ZNT 50MG RET, METOPROLOL - CT 50MG TABLEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Products: EBASTINA EG, EBASTEL 10MGCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Products: CITALOPRAM HEUMA 10MG NET, CITALOPRAM - CT 20MGMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalIt is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease … In 2010, it was estimated that 36 million people worldwide live with Alzheimer's Disease. In 2013, this number increased to 44 million.
Products: AXURA 5/10/15/20MG FILM ST, MEMANTIN HEU 10 MG FTA NETAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania.
Products: ARIP MT 10 TABLETS 10mg, ARIPIPRAZOL BETA 20MG