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Desvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigational[A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: EFEXOR® XR 150 MG. CAPSULAS DE LIBERACIÓN PROLONGADA, Ag-desvenlafaxineBeclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigational[A179839] Due to its anti-inflammatory, antipruritic, and anti-allergy properties, beclomethasone dipropionate is used in various inflammatory conditions, such as asthma, allergic rhinitis, and dermatoses … Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray.
Mixtures: INUVAIR 100/6UG 120 HUB DR, INUVAIR 100/6UG 120 HUB DRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … It is available as an extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and a twice-yearly gluteal injection.[L16168,L37744,L4137,L37749]
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: INVEGA SUSTENNA ® SUSPENSION DE LIBERACION PROLONGADA DE 150 MG, INVEGA SUSTENNA ® SUSPENSIÓN DE LIBERACIÓN PROLONGADA DE 50 MGGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234349] It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability. … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963.
Mixtures: BELOGENT %0,05+%0,1 KREM, 15 G, BELOGENT %0,05+%0,1 MERHEM, 15 GCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalTapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: PALEXIS® RETARD 150 MG, Nucynta ER Tablets 150 mgCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalA chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Products: ALLERGOCROM NAZAL SPREY, 15 ML, ALLERGO COMOD %2 15 ML NAZAL SPREYMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
Mixtures: Ag-sitagliptin Hydrochloride / Metformin, Ag-sitagliptin Hydrochloride / MetforminInternational brands: Nu-MetforminNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigationalsuch is used as a first-line treatment following diagnosis to slow down the progressive loss of lung function. … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OFEV 150 MG, OFEV® 150 MGLactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigationalLactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic … Organization's List of Essential Medicines as one of the most effective and safe medicines employed in a health system[L6205], data regarding its optimal place in therapy is often ambiguous.
Synonyms: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranoseProducts: LACTULOSE AL SIRUP, ORALAC 670 MG/ML ŞURUP, 150 MLAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136] … [L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: DM-AR, ARIPIPRAZOL AL 15 MG TAB