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Bosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalPhiladelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.
Synonyms: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrileProducts: BOSULİF 100 MG FİLM KAPLI TABLET, 30 ADET, XOLYXA® 100 MGBedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigational[A261856,A261861] It is the first drug that was approved in the last 40 years by the FDA for TB unresponsive to current treatments on the market. … [A261866] Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP synthase responsible for synthesizing ATP.
Synonyms: 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-olProducts: SIRTURO 100 MG, SIRTURO 100 MG TABLET, 24 ADETLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Mixtures: LACOMBI 30/10 MG KAPSUL, 28 ADET, LACOMBI 15/10 MG KAPSUL, 28 ADETProducts: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADACloxacillin
go.drugbank.com/drugs/DB01147ApprovedInvestigationalVet approvedA semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Synonyms: (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acidProducts: OXACIL GRANULES 125 MG/ 5 ML, CLOXACILLA POWDER FOR SYRUP 125 MG / 5 MLFamciclovir
go.drugbank.com/drugs/DB00426ApprovedInvestigationalIt is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Products: FAMVIR 125 MG TABLETAS, Famvir 125 mg - FilmtablettenCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalIt is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Products: CROMABAK EYE DROPS 20 mg/ml, VIVIDRIN EYE DROPS 20 mg/mlTetryzoline
go.drugbank.com/drugs/DB06764Approved[A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764] … [L32584, L32589, L32594] It is also used in combination with other drug classes, such as antihistamines, corticosteroids, and glucocorticoids in other countries.
Mixtures: EFEMOLINE 5 ML DAMLA, Visine Advanced Blister 6s PackProducts: RHİNOSİDE DAMLA, 10 ML, VISINE 0,5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 5 MLUdenafil
go.drugbank.com/drugs/DB06267ApprovedIt is not yet approved for use in the U.S., E.U., or Canada. … Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena.
Products: ZYDENA 100 MG, ZYDENA 100 MG FILM TABLET, 2 ADETFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and can also have effects at the androgen, progesterone, and glucocorticoid receptors.
Products: KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET, KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADETDiphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalAt high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. … When diphenoxylate is used alone, it is classified as a Schedule II.
Mixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 MLProducts: LOMOTIL 2,5 MG/0.025 MG TABLET, 20 ADET, LOMOTIL 2,5 MG/0.025 MG TABLET, 12 ADET