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Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigationalIn recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval.
Remimazolam
go.drugbank.com/drugs/DB12404ApprovedInvestigational[L14647] Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as [remifentanil], are designed to be metabolically fragile and thus
Lincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its h...
Bupivacaine
go.drugbank.com/drugs/DB00297ApprovedInvestigationalBupivacaine is a widely used local anesthetic agent.
Hydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigational[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]
Lemborexant
go.drugbank.com/drugs/DB11951ApprovedInvestigational[L10863] Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits, but rather an inability to … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance.
Categories: Orexin Receptor AntagonistsGamma-aminobutyric acid receptor subunit alpha-2
go.drugbank.com/bio_entities/BE0000381TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:29961870, PubMed:31032849). GABA-gated chloride channe...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-2Synonyms: GABA(A) receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0000471TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:14993607, PubMed:29961870, PubMed:30140029, PubMed:31056671). GABA-gate...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABA(A) receptor subunit alpha-5Gamma-aminobutyric acid receptor subunit alpha-3
go.drugbank.com/bio_entities/BE0000523TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:16412217, PubMed:29053855). GABA-gated chloride channels, also named GA...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-3Synonyms: GABA(A) receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-1
go.drugbank.com/bio_entities/BE0000795TargetHumansGABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-1Synonyms: GABA(A) receptor subunit alpha-1