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Pancuronium
go.drugbank.com/drugs/DB01337ApprovedA bis-quaternary steroid that is a competitive nicotinic antagonist. … As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Products: BROMURO DE PANCURONIO 4 MG/2 ML, BROMURO DE PANCURONIO 2 MG/MLTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigationalTamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.
Synonyms: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide, (R)-(−)-tamsulosinInternational brands: Harnal DChamomile
go.drugbank.com/drugs/DB14357ApprovedChamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Matricaria Recutita L. Flower, Matricariae FlosProducts: Soulagement De L'indigestionDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetinePaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.
Categories: Dopamine D2 Receptor Antagonists, P-glycoprotein inhibitorsSynonyms: 9-hydroxyrisperidoneButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedButylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Mixtures: DIPIRONA N- BULTILBROMURO DE HIOSCINA, N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 MLSynonyms: N-butylscopolammonium, N-butylscopolammonium ionOlea europaea pollen
go.drugbank.com/drugs/DB10378ApprovedOlea europaea pollen is the pollen of the Olea europaea plant. Olea europaea pollen is mainly used in allergenic testing.
Mixtures: Western 3 Tree Pollen Mix, Western 3 Tree Pollen MixSynonyms: Olea europaea pollen, european olive pollen extractVemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche. … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MGOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalDue to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life. … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat, 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolateFlubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Categories: Heterocyclic Compounds, 2-RingSynonyms: methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate, (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester