Search
Citicoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. … It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Synonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholineProducts: RONOCİT 1000 MG/4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, Citicor 1000 mg/4 mL IM/IV Enjeksiyonluk Çözelti (5 adet)Desipramine
go.drugbank.com/drugs/DB01151ApprovedThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: N-(3-methylaminopropyl)iminobibenzyl, 5-(γ-methylaminopropyl)iminodibenzylMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalTract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingProducts: MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial, Mitomycin C "Kyowa" 10 mg - TrockenstechampullenNicergoline
go.drugbank.com/drugs/DB00699ApprovedAn ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Categories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesSynonyms: 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate, (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester)Cyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigational[A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury. … [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.
Mixtures: Cyclo/Gaba 10/300 Pack, Cyclo/MagCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsTioconazole
go.drugbank.com/drugs/DB01007ApprovedTioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. … In addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166]
Mixtures: GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADET, TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADETCategories: 14-alpha Demethylase Inhibitors, Cytochrome P-450 CYP3A InhibitorsDapagliflozin
go.drugbank.com/drugs/DB06292ApprovedInvestigationalDapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. … [A261601] Dapagliflozin was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2 diabetes in conjunction with diet and exercise.
Mixtures: QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADET, XİGDUO XR 10 MG/ 1000 MG FİLM KAPLI TABLET, 28 TABLETCategories: Drugs Used in Diabetes, Sodium-Glucose Transporter 2 InhibitorsTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approved[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]
Mixtures: M-FURO MANT % 0.1 + % 1 KREM, 20G, Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalIt is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. … The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing.[L43397, L30335]
Products: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), MABCAMPATH ® 30 MG/MLOcrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigationalPrimary progressive multiple sclerosis (PPMS) accounts for 10-15% of the overall population of patients with MS, and leads to the gradual worsening of neurologic disability from symptom onset, often without … It was later approved by Health Canada in August 2017, making the drug the first available treatment for PPMS in both the US and Canada.
Products: OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET, OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET