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Displaying results 8991 - 9000 of 10000 in total
  1. Drug

    Zoxazolamine

    go.drugbank.com/drugs/DB19372
    ApprovedWithdrawn

    Synonyms: 2-amino-5-chlorobenzoxazole, 5-chloro-2-benzoxazolamineCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Syrosingopine

    go.drugbank.com/drugs/DB19379
    ApprovedWithdrawn

    Synonyms: -dimethoxy-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate 4-hydroxy, Yohimban-16-carboxylic acid, 18-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Miramistin ion

    go.drugbank.com/drugs/DB19386
    Investigational

    Miramistin ion is under investigation in clinical trial NCT05561816 (Efficacy and Safety of Dioxidin Versus Miramistin in Superficial Pyoderma).

    Synonyms: Benzenemethanaminium, n,n-dimethyl-n-(3-((1-oxotetradecyl)amino)propyl)-
  4. Drug

    Calcimycin

    go.drugbank.com/drugs/DB19408
    Investigational

    Primarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi. … Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis.

    Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingSynonyms: 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-4-benzoxazolecarboxylic acid
  5. Drug

    Azadirachtin

    go.drugbank.com/drugs/DB19419
    Investigational

    Azadirachtin is under investigation in clinical trial NCT06617026 (Short-term Outcome of Medical vs. Surgical Management of Chronic Anal Fissure).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Azadirachtin a
  6. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or … Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective

    Mixtures: Appbutamone-DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  7. Drug

    Bretylium

    go.drugbank.com/drugs/DB01158
    Approved

    The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. … Recent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.

    Mixtures: Bretylium Tosylate 0.4% and Dextrose 5% Inj, Bretylium Tosylate 0.2% and Dextrose 5% InjSynonyms: 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium, N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium
  8. Drug

    Terazosin

    go.drugbank.com/drugs/DB01162
    ApprovedInvestigational

    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831]. … Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837].

    Mixtures: Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg, Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mgCategories: P-glycoprotein inhibitors, Peripheral alpha-1 blockers
  9. Drug

    Procarbazine

    go.drugbank.com/drugs/DB01168
    ApprovedInvestigational

    An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.

    Synonyms: N-Isopropyl-α-(2-methylhydrazino)-p-toluamide, N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
  10. Drug

    Guanethidine

    go.drugbank.com/drugs/DB01170
    ApprovedWithdrawn

    It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.

    Synonyms: 2-(1-N,N-Heptamethyleneimino)ethylguanidine, N-(2-Perhydroazocin-1-ylethyl)guanidine