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Forasartan
go.drugbank.com/drugs/DB01342ExperimentalAs angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor BlockersPotassium cation
go.drugbank.com/drugs/DB01345ApprovedPotassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. … The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function.
Mixtures: Telom-X-geneSynonyms: potassium(1+), potassium(1+) ionSpirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalSpirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Tasosartan
go.drugbank.com/drugs/DB01349ExperimentalIt is used to treat patients with essential hypertension. … Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAprobarbital
go.drugbank.com/drugs/DB01352ExperimentalIllicitAprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-isopropylbarbituric acidButobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Categories: Heterocyclic Compounds, 1-RingLithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnIt is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Ephedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalEphedra is an alkaloid chemical compound traditionally obtained from the plant _Ephedra sinica_. … The drug is still sold in Canada in OTC formulations for respiratory conditions associated with bronchial asthma.
Mixtures: Miller's Formula No. 1Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic alpha-2 Receptor AgonistsAluminium
go.drugbank.com/drugs/DB01370ApprovedInvestigationalWithdrawnA metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
Aluminium monostearate
go.drugbank.com/drugs/DB01375ExperimentalAluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. … Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics.