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Pyrrolizidine
go.drugbank.com/drugs/DB19159InvestigationalPyrrolizidine is under investigation in clinical trial NCT05898373 (Vedicitumomab Alone or in Combination for the Treatment of Locally Advanced or Metastatic SDC).
Synonyms: 1-azabicyclo(3.3.0)octaneQuemliclustat
go.drugbank.com/drugs/DB19160InvestigationalQuemliclustat is under investigation in clinical trial NCT05329766 (A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1h-pyrazolo(3,4-b)pyridin-4-amine, 6-chloro-n-((1s)-1-(2-fluorophenyl)ethyl)-1-(5-o-(hydroxy(phosphonomethyl)phosphinyl)-.beta.-d-ribofuranosyl)-, 2-chloro-n6 -((1s)-1-(2-fluorophenyl)ethyl)-8-aza-1,7- dicarbaadenosine 5'-(trihydrogen 2-carbadiphosphate)(R)-Propafenone
go.drugbank.com/drugs/DB19162InvestigationalPropafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
Synonyms: 1-propanone, 1-(2-((2r)-2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, (R)-propafenonePF-06835919
go.drugbank.com/drugs/DB19163InvestigationalPF-06835919 is under investigation in clinical trial NCT05463575 (Ketohexokinase Inhibition in NAFLD).
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: (1α,5α,6α)-3-[2-[(2S)-2-Methyl-1-azetidinyl]-6-(trifluoromethyl)-4-pyrimidinyl]-3-azabicyclo[3.1.0]hexane-6-acetic acid, 2-((1S,5R)-3-(2-((2S)-2-METHYLAZETIDIN-1-YL)-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-YL)-3-AZABICYCLO(3.1.0)HEXAN-6-YL)ACETIC ACIDPhenazepam
go.drugbank.com/drugs/DB19164InvestigationalPhenazepam is under investigation in clinical trial NCT03017430 (Pregabalin for Opiate Withdrawal Syndrome).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-bromo-5-(2-chlorophenyl)-, 2h-1,4-benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-Pixatimod
go.drugbank.com/drugs/DB19166InvestigationalPixatimod is under investigation in clinical trial NCT05061017 (Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide
Poloxamine 1304
go.drugbank.com/drugs/DB19167InvestigationalPoloxamine 1304 is under investigation in clinical trial NCT00483795 (Pilot Evaluation of Two Multipurpose Solutions in Regards to Corneal Staining).
Dexamethasone palmitate
go.drugbank.com/drugs/DB19168InvestigationalDexamethasone palmitate is under investigation in clinical trial NCT05693467 (Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery).
Synonyms: 9-fluoro-11,17-dihydroxy-16-methyl-21-((1- oxohexadecyl)oxy)pregna-1,4-diene-3,20-dione (11.beta.,16.alpha.)-PXS-4728A free base
go.drugbank.com/drugs/DB19177InvestigationalPXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder).
Synonyms: Benzamide, 4-(((2e)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-n-(1,1-dimethylethyl)-OSU-6162
go.drugbank.com/drugs/DB19178InvestigationalOSU-6162 is under investigation in clinical trial NCT05641623 (OSU6162 as Add-on in Ssri/snri-resistant Depression).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors