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Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalmutations, or ALK, ROS1 or RET genomic tumour aberrations. … [L32868] Sugemalimab was under investigation in the clinical trial NCT03802591 (A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-esophageal Junction Adenocarcinoma).
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsPafolacianine
go.drugbank.com/drugs/DB15413ApprovedInvestigationalPafolacianine, or OTL38, is a folate analogue conjugated with a fluorescent dye that absorbs light in the near-infrared (NIR) spectrum [A242572] within a range of 760 nm to 785 nm, with a peak absorption … It emits fluorescence within a range of 790 nm to 815 nm with a peak emission of 796 nm.
Categories: Compounds used in a research, industrial, or household settingFormaldehyde
go.drugbank.com/drugs/DB03843ApprovedVet approvedA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. … In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative.
Mixtures: British Army Foot PwrCategories: Compounds used in a research, industrial, or household settingReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalIL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. … It is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines. Reslizumab is marketed as Cinqaero in Europe.
Categories: Drugs for Obstructive Airway DiseasesTetryzoline
go.drugbank.com/drugs/DB06764Approved[A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764] … Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, Visine.
Mixtures: ISCHEMOL A, ISCHEMOL ACategories: Compounds used in a research, industrial, or household settingVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalof a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia. … of a condition like achondroplasia.
Categories: Drugs for Treatment of Bone DiseasesFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Categories: Antihypertensive Agents Indicated for HypertensionProducts: FOSINOPRIL NaHydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications. … [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.
Categories: Antihypertensive Agents Indicated for HypertensionProducts: APRESOLINE FOR INJECTION 20 mg/ampouleLotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approvedLotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. … [A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551]
Cholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnCholecystokinin ( also known as _CCK or CCK-PZ_) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. … Recent studies have suggested that cholecystokinin also plays a major role in inducing drug tolerance to opioids such as morphine and heroin, and is partially implicated in experiences of pain hypersensitivity
Categories: Tests for Pancreatic Function