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Dimethicone 410
go.drugbank.com/drugs/DB14005Approved[L2162] The name dimethicone has a lot of nomenclature inconsistencies as it is used to refer to common names, generic names, trade names or even for the listing of mixtures. … [A32462] It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit.
Nimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalNimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Phenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalIt is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.
Mixtures: EGOPSORYL TA GEL, EGOPSORYL TA GELChlorpromazine
go.drugbank.com/drugs/DB00477ApprovedInvestigationalVet approvedLike the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. … Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Coagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalInherited factor X deficiency is a rare autosomal recessive bleeding disorder that is estimated to occur in 1:1 000 000 individuals up to 1:500 carriers [A31471]. … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency.
Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETEucalyptus oil
go.drugbank.com/drugs/DB11114ApprovedIt is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions. … It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response.
Mixtures: Zam-Buk Ointment, Cellzyme ON-TOXInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnInositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. … [L2560] Inositol can be found as an ingredient of OTC products by Health Canada but all current product whose main ingredient is inositol are discontinued.
Mixtures: Super Daily No 2, Protect Plus SO 60Olanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigational[A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to
International brands: CO OlanzapineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeE3 ubiquitin ligase TRAF3IP2
go.drugbank.com/bio_entities/BE0011632TargetHumansTransfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828). … Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B
Synonyms: Connection to IKK and SAPK/JNK