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Tolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Categories: Compounds used in a research, industrial, or household settingProducts: POTEX 880 MG / 1 G GRANÜL, 20 ADET, JUVELTA 880 MG/1 G GRANÜL, 20 SAŞERomiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalRomiplostim is produced by recombinant DNA technology in Escherichia coli. FDA approved on August 22, 2008. … Each subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl.
Products: ROMIPLATE 250 MCG, NPLATE® 250 MCGAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnIt was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. … Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms.
Mixtures: ANTIGRIP 2000Products: ASTEMIZOL SUSPENSION 100 MG, AZTEMIZOL SUSPENSION 1 MG/MLAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalAlemtuzumab is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.[L43397] Alemtuzumab was approved by the FDA in 2001. … The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G).
Products: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), MABCAMPATH ® 30 MG/MLRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalRopivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin.
Synonyms: L-N-n-propylpipecolic acid-2,6-xylidideProducts: ROVANAEST 2.0 (Ropivacaine Hydrochloride 2mg/mL Solution for Injection or Infusion USP), Braun 5 mg/ml InjektionslösungZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … In addition, zolpidem improves sleep quality in patients suffering from chronic insomnia and can show mild muscle relaxant properties [L5584].
Synonyms: N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamideProducts: ZOLPIDEM EG, Zolpidem Tartrate ERInfluenza B virus B/Brisbane/60/2008 antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB11044ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Synonyms: Influenza B virus B/Brisbane/60/2008 antigen (propiolactone inactivated)Mixtures: Medical Provider Single Use EZ Flu Shot Afluria 2016-2017, Medical Provider Single Use EZ Flu Shot Fluvirin 2016-2017Afatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalFor oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected … by an FDA-approved test [L2939].
Products: GIOTRIF® 20 MG, GIOTRIF 20 MG FILM KAPLI TABLET ,TABLET, 28 ADETTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigationalreceptor inhibitor (SNRIs) in the treatment of depression. … [T646] It was initially granted FDA approval in 1981.[L3484]
Products: DESYREL XL 300 MG UZATILMIŞ SALIMLI FİLM TABLET , 20 TABLET, DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 20 TABLETPilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigational[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors.
Mixtures: E-pilo-2 Oph Soln, E-pilo-6 Oph SolnProducts: Ocusert Pilo 20, SALAGEN ® 7.5 MG