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Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...
Mixtures: E-pilo-2 Oph Soln, E-pilo-6 Oph SolnProducts: Ocusert Pilo 20, SALAGEN ® 7.5 MGBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigational[A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE. … [L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib.[A204083] Bortezomib was first synthesized in 1995.
Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProducts: BOTEMIB 1.0 MG, BORTEZOMIB EGRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigational[A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. … [A31328] It is a diarylpyrimidine derivative.
Mixtures: ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET, ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADETSynonyms: 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrilePegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigational[A187607] First developed by Amgen, pegfilgrastim was initially approved by the FDA in 2002 and marketed as Neulasta. It is typically administered via a subcutaneous injection. … [A187631] Due to the relatively short circulating half-life of filgrastim, a 20 kDa PEG moiety was covalently conjugated to the N-terminus of filgrastim (at the methionine residue) to develop longer-acting
Synonyms: PEG-G-CSF, Pegylated G-CSFProducts: ZIEXTENZO® 6 MG SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, NEULASTIM ® SOLUCION INYECTABLE 6 MG/0.6 MLRufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Products: INOVELON FILM-COATED TABLET 200 MG, Inovelon 200 mg film-coated tabletsDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.
International brands: Digocard-GProducts: LANOXIN 250 MICROGRAMS TABLET, LANOXIN INJECTION 0.5 mg/2 mlVincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalIt is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. … malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone–marrow suppression (at
Products: VINCRISTINA EG, SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE.Bedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigational[A261866] Consequently, bedaquiline can be used to treat mycobacterial infection, particularly tuberculosis (TB). … [A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate combination regimen.[L48506,A261866]
Products: SIRTURO 100 MG, SIRTURO 100 MG TABLET, 24 ADETFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A39743] In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout.
Products: FEBUXOSTAT EG, ADENURIC 120 MGHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[A185138] It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.
Mixtures: LOSARTAN / HCT 100/25 MG, Hyzaar Tablet 100 / 12.5 mgProducts: Hydrochlorothiazide 100 Tab, HCT - CT 12.5 MG TABLETTEN