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Ceftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigationalBacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding … [A232920, A232925, A232930] Ceftazidime is a third-generation cephalosporin with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as _Pseudomonas aeruginosa
Cerivastatin
go.drugbank.com/drugs/DB00439ApprovedWithdrawnFood and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal rhabdomyolysis, a severe adverse reaction from
Gemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalGemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose.
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE, VIRULIZIN® 1G POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLETeniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalTeniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexInternational brands: Bang LaiMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor.
Imipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. … In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: AA PHARMA IMIPRAMINE TABLET 10MG, AA PHARMA IMIPRAMINE TABLET 25MGMetharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnMetharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Sodium tetradecyl sulfate
go.drugbank.com/drugs/DB00464ApprovedAn anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Categories: Compounds used in a research, industrial, or household settingQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalIt was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
Fluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approvedFluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).
Products: FLUOXETIN AL 20MG TABL, FLUOXETIN 10 1A PHARMA