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Displaying results 9131 - 9140 of 10000 in total
  1. Drug

    Tunodafil

    go.drugbank.com/drugs/DB21576
    Investigational

    The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. … Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol). Tunodafil has a monoisotopic molecular weight of 487.23 Da.

  2. Drug

    Tamuzimod

    go.drugbank.com/drugs/DB21621
    Investigational

    The usage of the INN stem '-imod' in the name indicates that Tamuzimod is a immunomodulator, both stimulant/suppressive and stimulant. … Tamuzimod is under investigation in clinical trial NCT05156125 (VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis).

  3. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor. … Neladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC).

    Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)
  4. Drug

    Streptolydigin

    go.drugbank.com/drugs/DB04785
    Experimental

    Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

  5. Drug

    WVE-003

    go.drugbank.com/drugs/DB17870
    Investigational

    WVE-003 is an allele-selective antisense oligonucleotide that works to selectively reduce the toxic mutant huntingtin (mHTT) protein.[L46787]

  6. Drug

    PNT001

    go.drugbank.com/drugs/DB18375
    Investigational

    PNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.

  7. Drug

    BBT-877

    go.drugbank.com/drugs/DB18668
    Investigational

    BBT-877 is an autotaxin enzyme inhibitor being investigated for the treatment of fibrotic diseases, such as idiopathic pulmonary fibrosis.

  8. Drug

    Mavelertinib

    go.drugbank.com/drugs/DB16228
    Investigational

    Mavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).

  9. Drug

    DCVax-L

    go.drugbank.com/drugs/DB17580
    Investigational

    DCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded _in vitro_ with autologous tumour lysate.

  10. Drug

    EF-022

    go.drugbank.com/drugs/DB17768
    Investigational

    EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.

    Synonyms: EF 022