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Displaying results 9141 - 9150 of 10000 in total
  1. Drug

    Elamipretide

    go.drugbank.com/drugs/DB11981
    ApprovedInvestigational

    [A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.

  2. Drug

    Nirogacestat

    go.drugbank.com/drugs/DB12005
    ApprovedInvestigational

    Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … granted breakthrough therapy, fast track, and orphan drug designations for the treatment of desmoid tumors, and the final approval was based on positive results obtained in the Phase 3 DeFi trial, where a

  3. Drug

    Ozagrel

    go.drugbank.com/drugs/DB12017
    Investigational

    Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.

    Categories: Thromboxane-A Synthase, antagonists & inhibitors
  4. Drug

    Pardoprunox

    go.drugbank.com/drugs/DB12061
    Investigational

    Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.

  5. Drug

    Sisomicin

    go.drugbank.com/drugs/DB12604
    Investigational

    Sisomicin has been used in trials studying the treatment of Pyoderma.

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  6. Drug

    Meclocycline

    go.drugbank.com/drugs/DB13092
    Investigational

    Meclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .

  7. Drug

    Clobetasone

    go.drugbank.com/drugs/DB13158
    Approved

    Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions

  8. Drug

    Flutrimazole

    go.drugbank.com/drugs/DB13425
    Investigational

    Flutrimazole is a topical imidazole antifungal agent with broad spectrum activity.[A275033]

  9. Drug

    Cefodizime

    go.drugbank.com/drugs/DB13470
    Investigational

    Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity.[A275053, A275058]

  10. Drug

    Cefpirome

    go.drugbank.com/drugs/DB13682
    Approved

    Cefpirome is a β-lactam or cephalosporin.[A249055]