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Displaying results 911 - 920 of 10000 in total
  1. Drug

    Sertraline

    go.drugbank.com/drugs/DB01104
    ApprovedInvestigational

    Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. … Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.

    Synonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitors
  2. Drug

    Zapomeran

    go.drugbank.com/drugs/DB21761
    Approved

    Zapomeran, marketed under the brand name Kostaive (ARCT-154), is a self-amplifying mRNA COVID-19 vaccine for individuals 18 years and older. … [L52580,L52390] The self-amplifying nature of the vaccine is due to the mRNA additionally encoding a replicase enzyme, which creates more copies of the mRNA itself once inside the cell.

  3. Drug

    Eosin

    go.drugbank.com/drugs/DB13706
    Investigational

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingProducts: EOSINA NA
  4. Target

    Dihydropteroate synthase type-1

    go.drugbank.com/bio_entities/BE0000120
    TargetMycobacterium fortuitum

    Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (By similarity). Implicated in resist...

    Synonyms: Dihydropteroate synthase type I, Dihydropteroate pyrophosphorylase type I
  5. Target

    Hexokinase-1

    go.drugbank.com/bio_entities/BE0001108
    TargetEnzymeHumans

    Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6...

    Synonyms: HK I, Hexokinase type I
  6. Indication

    Hypokalemic Periodic Paralysis

    go.drugbank.com/conditions/DBCOND0002204
    Drugs: Diclofenamide
    Synonyms: Periodic paralysis I
  7. Drug

    Combretastatin A4

    go.drugbank.com/drugs/DB14680
    Experimental

    Synonyms: CA4, PHENOL, 2-METHOXY-5-(2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-, (Z)-
  8. Target

    Cag alpha

    go.drugbank.com/bio_entities/BE0002850
    TargetHelicobacter pylori

    Polypeptides: Cag alphaSynonyms: Cag-alfa, cag-alpha
  9. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705

    Synonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidineCategories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 2-Ring
  10. Target

    Cellular retinoic acid-binding protein 1

    go.drugbank.com/bio_entities/BE0000508
    CarrierTransporterTargetHumans

    Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors

    Synonyms: CRABP-I, Cellular retinoic acid-binding protein I