Search

Displaying results 911 - 920 of 10000 in total
  1. Drug

    Zapomeran

    go.drugbank.com/drugs/DB21761
    Approved

    Zapomeran, marketed under the brand name Kostaive (ARCT-154), is a self-amplifying mRNA COVID-19 vaccine for individuals 18 years and older. … [L52580,L52390] The self-amplifying nature of the vaccine is due to the mRNA additionally encoding a replicase enzyme, which creates more copies of the mRNA itself once inside the cell.

  2. Drug

    Sertraline

    go.drugbank.com/drugs/DB01104
    ApprovedInvestigational

    Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. … Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitorsSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
  3. Drug

    Eosin

    go.drugbank.com/drugs/DB13706
    Investigational

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingProducts: EOSINA NA
  4. Target

    Dihydropteroate synthase type-1

    go.drugbank.com/bio_entities/BE0000120
    TargetMycobacterium fortuitum

    Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (By similarity). Implicated in resist...

    Synonyms: Dihydropteroate synthase type I, Dihydropteroate pyrophosphorylase type I
  5. Target

    Hexokinase-1

    go.drugbank.com/bio_entities/BE0001108
    TargetEnzymeHumans

    Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6...

    Synonyms: HK I, Hexokinase type I
  6. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 2-RingSynonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidine
  7. Indication

    Hypokalemic Periodic Paralysis

    go.drugbank.com/conditions/DBCOND0002204
    Drugs: Diclofenamide
    Synonyms: Periodic paralysis I
  8. Target

    Cag alpha

    go.drugbank.com/bio_entities/BE0002850
    TargetHelicobacter pylori

    Polypeptides: Cag alphaSynonyms: Cag-alfa, cag-alpha
  9. Target

    Cellular retinoic acid-binding protein 1

    go.drugbank.com/bio_entities/BE0000508
    CarrierTransporterTargetHumans

    Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors

    Synonyms: CRABP-I, Cellular retinoic acid-binding protein I
  10. Target

    GTP cyclohydrolase 1

    go.drugbank.com/bio_entities/BE0001055
    TargetEnzymeHumans

    Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function ...

    Synonyms: GTP-CH-I, GTP cyclohydrolase I