Search
Metformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...
Levonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalLevonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy. Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released fr...
Products: ONIVE 1® 1.5 MG TABLETA, ONIVE 2® 0.75 MG TABLETASDiethylamino hydroxybenzoyl hexyl benzoate
go.drugbank.com/drugs/DB11269ApprovedDiethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenz...
Mixtures: Wonder Intensive BBCream 21 (Light)Rineterkib
go.drugbank.com/drugs/DB17560InvestigationalRineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel
Ubrogepant
go.drugbank.com/drugs/DB15328ApprovedInvestigational[erenumab], [fremanezumab], [galcanezumab]) have also been approved in recent years.[A189207] Ubrogepant was approved by Health Canada on November 10, 2022. … [A189195] They appear to be better tolerated, do not contribute to medication overuse headaches, and carry no apparent cardiovascular risk, making them suitable for use in patients with cardiovascular
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsDeutivacaftor
go.drugbank.com/drugs/DB15141ApprovedInvestigationalDeutivacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It is used alongside CFTR correctors to increase the quantity and function of CFTR at the cell surface in patients with cystic fibr...
High affinity immunoglobulin epsilon receptor subunit gamma
go.drugbank.com/bio_entities/BE0000049TargetHumansAs a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. … As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit gammaSynonyms: Fc receptor gamma-chain, IgE Fc receptor subunit gammaGamma-aminobutyric acid receptor subunit rho-1
go.drugbank.com/bio_entities/BE0000129TargetHumansRho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (PubMed:37659407). Rho-containing GABA-gated chlorid...
Polypeptides: Gamma-aminobutyric acid receptor subunit rho-1Synonyms: GABA(C) receptor, GABA(A) receptor subunit rho-1Mast/stem cell growth factor receptor Kit
go.drugbank.com/bio_entities/BE0000453TargetHumansKIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. … Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.
Polypeptides: Mast/stem cell growth factor receptor KitGamma-aminobutyric acid receptor subunit alpha-4
go.drugbank.com/bio_entities/BE0000478TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:35355020). GABA-gated chloride channels, also named GABA(A) receptors (...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-4Synonyms: GABA(A) receptor subunit alpha-4