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Sigma intracellular receptor 2
go.drugbank.com/bio_entities/BE0015084TargetHumansSigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking
Polypeptides: Sigma intracellular receptor 2Synonyms: Sigma2 receptor, Sigma-2 receptorChemerin-like receptor 1
go.drugbank.com/bio_entities/BE0019036TargetHumansReceptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1.
Polypeptides: Chemerin-like receptor 1Synonyms: Chemokine-like receptor 1, G protein-coupled receptor DEZMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalMagnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite.
Mixtures: ConRx AR, Mag-AlBemotrizinol
go.drugbank.com/drugs/DB11206ApprovedBemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. … Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.
Mixtures: Spa Skilha Helioprot Ab SPF 40, Ruby-Cell 4U Plus SunTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalAs recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate.
Evinacumab
go.drugbank.com/drugs/DB15354ApprovedInvestigationalThe ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in recent years. … rationale for the development of a therapy targeted against ANGPTL3.
Abiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1, Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibodyEndothelin receptor type B
go.drugbank.com/bio_entities/BE0000043TargetHumansNon-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective typeMuscarinic acetylcholine receptor M3
go.drugbank.com/bio_entities/BE0000045TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1
go.drugbank.com/bio_entities/BE0000092TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activity