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Budigalimab
go.drugbank.com/drugs/DB16668InvestigationalBudigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination … With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
PI-166
go.drugbank.com/drugs/DB05859ExperimentalIt has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.
RGN6024
go.drugbank.com/drugs/DB33059ExperimentalRGN6024, also known as RGN-6024 or RGNi6024, is a synthetic small-molecule tubulin destabilizer from Reglagene. … Preclinical characterization reports that RGN6024 binds the colchicine-binding site of beta-tubulin, inhibits microtubule polymerization in biochemical and cellular assays, induces G2/M arrest in glioblastoma
EB05
go.drugbank.com/drugs/DB16477InvestigationalEB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.
Synonyms: Immunoglobulin G1 [326-serine,329-phenylalanine,de-448-lysine], anti-(human Toll-like receptor 4) (human-Mus musculus monoclonal EB05 γ1-chain), disulfide with human-Mus musculus monoclonal EB05 κ-chainPegapamodutide
go.drugbank.com/drugs/DB14817InvestigationalPegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).
Erteberel
go.drugbank.com/drugs/DB07933InvestigationalErteberel is an estrogen receptor beta agonist that has been used in trials studying the treatment of Benign Prostatic Hyperplasia.
Synonyms: (3aS,4R,9bR)-4-(4-Hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta(c)(1) benzopyran-8-olPurslane
go.drugbank.com/drugs/DB14327ApprovedPurslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
ORE-1001
go.drugbank.com/drugs/DB12271InvestigationalORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.
Technetium Tc-99m arcitumomab
go.drugbank.com/drugs/DB00113ExperimentalThe molecule has a molecular weight of ~54,000 Daltons. … Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99.
Sulesomab
go.drugbank.com/drugs/DB13976ApprovedMarket product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.