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Displaying results 921 - 930 of 7181 in total
  1. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    [A229853, A229923] Temozomolide as an adjunct to radiotherapy followed by maintenance dosing remains the standard of care for both Glioblastoma and refractory anaplastic astrocytoma. … Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to

    Products: TEMODAL 2.5 MG/ML İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 1 ADET
  2. Drug

    Insulin icodec

    go.drugbank.com/drugs/DB16693
    ApprovedInvestigational

    [L51078]The US FDA subsequently approved insulin icodec in March 2026 for use as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. [L56102] … It is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life.

  3. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    [L7961] It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. … Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative.

    Synonyms: 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid, 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acidProducts: Nu-furosemide Tablets
  4. Indication

    Gout Flares

    go.drugbank.com/conditions/DBCOND0059958
    Drugs: Acetaminophen · Azapropazone · Benzbromarone · Betamethasone · Betamethasone phosphate · Bupivacaine +25 more
    Synonyms: Arthritis due to gout, Arthritis of great toe due to gout
  5. Drug

    Lonapegsomatropin

    go.drugbank.com/drugs/DB16220
    ApprovedInvestigational

    11.5 kg, with growth failure due to insufficient growth hormone secretion. … [L36380] It was later approved by the European Commission on 13 January 2022.[L39900]

  6. Drug

    Varicella zoster vaccine (recombinant)

    go.drugbank.com/drugs/DB13924
    ApprovedInvestigational

    One of the most common complications associated with shingles is the development of Post-Herpetic Neuralgia (PHN), a persistant severe nerve pain that develops as a result of chronic pain from shingles … Shingrix also contains an adjuvant system, AS01B, which is intended to enhance the immunological response to the vaccine leading to longer lasting and greater immunogenicity to the herpes zoster virus

  7. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion. … [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries.

    Products: RANIDURA T 150MG, RANIDURA T 300MG
  8. Indication

    Eclampsia

    go.drugbank.com/conditions/DBCOND0000607
    Drugs: Cocarboxylase
    Synonyms: Eclampsia, unspecified as to time period
  9. Target

    Serine/threonine-protein kinase/endoribonuclease IRE1

    go.drugbank.com/bio_entities/BE0003839
    TargetHumans

    The endoribonuclease activity is specific for XBP1 mRNA and excises 26 nucleotides from XBP1 mRNA (PubMed:11779464, PubMed:21317875, PubMed:24508390). … In unstressed cells, the endoplasmic reticulum luminal domain is maintained in its inactive monomeric state by binding to the endoplasmic reticulum chaperone HSPA5/BiP (PubMed:21317875).

    Synonyms: Endoplasmic reticulum-to-nucleus signaling 1
  10. Indication

    Aspiration Pneumonia

    go.drugbank.com/conditions/DBCOND0031880
    Drugs: Prednisolone
    Synonyms: Pneumonitis due to inhalation of food and vomit