Gout Flares (DBCOND0059958)

Identifiers

Synonyms
Gouty Arthritis (GA) / Acute Gouty Arthritis / Acute Gout / Gout Acute / Gout attack / Acute attacks of gout / Gout flare / Acute flares / Acute attacks / Arthritis, Gouty / Gout / Gouty Arthritis / Idiopathic gout / Acute gout (disorder) / Primary gout (disorder) / Arthritis gouty / Arthritis due to gout (disorder) / Gouty arthropathy / Gouty arthropathy (disorder) / Articular gout / Joints gout affected (finding) / Gout, unspecified / Inflammatory disorder due to increased blood urate level (disorder) / Podagra / Arthritis of great toe due to gout (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Acetaminophen
An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
Allopurinol
A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
Azapropazone
Not Available
Benzbromarone
A uricosuric agent which is taken daily for the prevention of gout flares.
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Betamethasone phosphate
A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Bupivacaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Canakinumab
An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA).
Citric acid
An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
Colchicine
An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.
Corticotropin
A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Dexketoprofen
An NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
Diclofenac
An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Etoricoxib
A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
Febuxostat
A xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol.
Fenbufen
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
Hydrocortisone
A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Hydrocortisone succinate
A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Ibuprofen
An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
Indomethacin
A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Lesinurad
A uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
Meclofenamic acid
An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Methocarbamol
A CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Methylprednisolone hemisuccinate
A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Naproxen
An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
Niflumic acid
A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
Potassium citrate
An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
No drug targets
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Probenecid
A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Sodium citrate
An ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
Sulfinpyrazone
A platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
Sulindac
An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
Tetracosactide
A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Triamcinolone
A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06451848
A Bioequivalence Study of Two Different Dosage Form of GenakumabNo drug interventionsother1recruiting
NCT06273813
Treatment of Topical Ketorolac Gel in Acute Gouty Flaretreatment1not_yet_recruiting
NCT00170781
Efficacy and Safety of Lumiracoxib 400 mg Once Daily in Acute Flares of Gouttreatment4completed
NCT01356602
Safety and Efficacy of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patientstreatment3completed
NCT02545777
The Clinical Study on Treating Acute Gouty Arthritis Using Both Internal and External Therapy of Tonifying Spleen and Descending Turbidtreatment2unknown_status
NCT03002974
A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritistreatment2completed
NCT01593527
Canakinumab in the Treatment of Gouty Arthritis Flare(s) and Prevention of New Flares in Patients With Chronic Kidney Diseasetreatment3withdrawn
NCT01431638
Long-Term Safety and Tolerability of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patientstreatment3completed
NCT05983445
Safety & Efficacy of Genakumab in Patients With Frequent Flarestreatment3recruiting
NCT00142558
A Study Evaluating the Effect of Etoricoxib and Indomethacin in the Treatment of Acute Gout (0663-081)(COMPLETED)treatment4completed
NCT01080131
Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicines Including a 12 Week Extension and a 1 Year Open-label Extension Study.treatment3completed
NCT02674776
Efficacy and Safety of HuZhen Capsule for Treatment of Patients With Acute GoutNo drug interventionstreatment3unknown_status
NCT06169891
A Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gouttreatment3not_yet_recruiting
NCT05936268
Safety and Efficacy of Genakumab for Injection in Patients With Gout Flaretreatment2recruiting
NCT00798369
Targeted Dose Finding of Canakinumab (ACZ885) for Management of Acute Flare in Refractory or Contraindicated Gout Patientstreatment2completed
NCT01029652
Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicine Including a 12 Weeks Extension and an Open-label 48 Weeks Extension Studytreatment3completed
NCT05925166
Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ Fusion Protein in the Treatment of Acute GouttreatmentNot Availablenot_yet_recruiting
NCT05328531
Clinical Study of Genakumab for Injection in Patients With Acute GoutNo drug interventionstreatment1 / 2unknown_status
NCT05698680
Prednisolone Versus Colchicine for Acute Gout in Primary Caretreatment4recruiting
NCT05936281
Safety and Efficacy of Genakumab for Injection in Patients With Gout Initiating Urico-lowering Therapytreatment2not_yet_recruiting
NCT00997581
Apremilast Therapy for Acute Gouty Arthritistreatment2withdrawn
NCT05588908
A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gouttreatment1 / 2recruiting
NCT01310673
Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gouttreatment4completed
NCT04306653
ACTH vs Betamethasone in Hospitalized Patients With Acute GouttreatmentNot Availableunknown_status
NCT03621215
The Effect of Tart Cherry Juice on Risk of Gout AttacksNo drug interventionstreatmentNot Availableterminated
NCT05658575
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flaretreatment2 / 3recruiting
NCT03636373
Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gouttreatment4terminated
NCT04067492
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attacktreatment2terminated
NCT06444867
A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968No drug interventionstreatment1recruiting
NCT01712204
A Proof-of-Concept Study of AC-201 to Prevent Gout Flaresprevention2completed
NCT05256303
Rural Hospital-Level Care at Home for Acutely Ill AdultsNo drug interventionstreatmentNot Availablecompleted
NCT04784351
Prediction of Expected Length of Hospital Stay Using Machine LearningNo drug interventionsNot AvailableNot Availableunknown_status
NCT05586971
Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patientstreatment3recruiting
NCT03933007
Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flaretreatment4terminated
NCT03203759
Hospital-Level Care at Home for Acutely Ill AdultsNo drug interventionstreatmentNot Availablecompleted
NCT04080570
Remote Physician Care for Home Hospital PatientsNo drug interventionstreatmentNot Availablecompleted
NCT05045742
Prediction of Patient Deterioration Using Machine LearningNo drug interventionsNot AvailableNot Availableunknown_status
NCT04069325
Efficacy and Safety of Simiaowan in Prevention of Acute Flares in Chronic Gout Patients Initiating Febuxostat TherapypreventionNot Availableunknown_status
NCT04531280
Rural Home Hospital: Proof of ConceptNo drug interventionstreatmentNot Availablecompleted
NCT05522504
Distribution of Immune Cells and Their Subtypes in Peripheral Blood of GoutNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04849312
Prediction of 30-Day Readmission Using Machine LearningNo drug interventionsNot AvailableNot Availableunknown_status
NCT06207045
The Effects of Limb Elevation During Gout Flare EpisodesNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06197828
Novel Biomarkers for Early Renal Injury in Children With SepsisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05586958
Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patientstreatment3recruiting
NCT03524222
Home Hospital for Suddenly Ill AdultsNo drug interventionstreatmentNot Availableunknown_status
NCT05253833
Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination with Allopurinol in Patients with Tophaceous Gouttreatment2active_not_recruiting
NCT06439602
Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout PatientsNo drug interventionstreatment3recruiting
NCT00549549
Celebrex In Acute Gouty Arthritis Studytreatment3completed
NCT05119686
Phase 2b Evaluation of Efficacy and Safety of AR882 in Gout PatientsNo drug interventionstreatment2completed
NCT05966701
The MAD Study of SSGJ-613 in Healthy SubjectsNo drug interventionstreatment1not_yet_recruiting
NCT00663169
Efficacy and Safety of a Single Dose of Canakinumab (ACZ885) in Hospitalized Patients With Acute Gouttreatment2completed
NCT04733079
Treat-to-target by Email During Urate-lowering Therapy in GoutNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05289544
Phone-Based Based Walk with Ease Program for Adults with ArthritisNo drug interventionssupportive_careNot Availablecompleted
NCT06229145
A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gouttreatment4recruiting
NCT06629376
Safety, Tolerability, and Pharmacokinetic Characteristics of SSS11 in Patients With Gout and Hyperuricemiatreatment1recruiting
NCT06622603
The Effects of Febuxostat Dose Tapering in Gout Patients Optimally Controlled for 5 Years or Moretreatment4not_yet_recruiting
NCT04875702
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gouttreatment4recruiting
NCT04844814
Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantationtreatment2recruiting
NCT05507723
Tight Control of Gouty Arthritis Compared to Usual CareNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT05818085
Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gouttreatment2 / 3active_not_recruiting
NCT06276556
Extension Study of ABP-671 in Participants With Gouttreatment2 / 3terminated
NCT06501534
A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjectstreatment2active_not_recruiting
NCT04075903
Gout in the ED and Improving Research ParticipationNo drug interventionstreatmentNot Availablerecruiting
NCT04900090
Tahiti-families: Polynesian Families of Gout PatientsNo drug interventionsotherNot Availablecompleted
NCT01265264
Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinoltreatment2completed
NCT02037321
Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic RiskNo drug interventionsNot AvailableNot Availableunknown_status
NCT04519021
Knowledge, Attitude and Practice Regarding Diagnosis and Management of Gout Among Clinicians in NepalNo drug interventionsNot AvailableNot Availablecompleted
NCT04697602
Low-dose Colchicine With or Without Stepwise Dose Titration of Febuxostat for Flare Prophylaxis in GouttreatmentNot Availableterminated
NCT01416402
Open Label Safety/Efficacy Study of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Gout Patientstreatment2completed
NCT01988402
Does Allopurinol Prolong a Treated, Acute Gout Flare?treatment4completed
NCT01508702
Lesinurad Monotherapy in Gout Subjects Intolerant to Xanthine Oxidase Inhibitorstreatment3completed
NCT03470584
Vegetarian Diet and Chronic Degenerative DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT01744379
Single and Multiple Dose Study in Japanesetreatment1completed
NCT02702479
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic RiskNo drug interventionsNot AvailableNot Availableunknown_status
NCT03416543
Effect of a New BI-specifiC Antibody Towards Dendritic Cells on Inflammation in Rheumatoid ArthritisNo drug interventionsNot AvailableNot Availablecompleted
NCT01052987
Study of Tranilast Alone or in Combination With Allopurinol in Subjects With Hyperuricemiatreatment2completed
NCT01519687
Study of Levotofisopam 50 mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gouttreatment2unknown_status
NCT06534554
Improving Gout Care After an ED VisitNo drug interventionshealth_services_researchNot Availablerecruiting
NCT03847753
Exploring the Comorbidity Between Mental Disorders and General Medical ConditionsNo drug interventionsNot AvailableNot Availablecompleted
NCT03927677
The Effect of Colchicine on the Pharmacokinetic Profile of LC350189 in Healthy Aldults.treatment1completed
NCT01038947
Safety and Efficacy Study of Intramuscular Uricase-PEG 20treatment1unknown_status
NCT01356498
Open-Label Extension Study for Patients Who Completed a Phase 3 Double-blind Study of PEG-uricase for Symptomatic Gouttreatment3completed
NCT01775098
Allopurinol in Acute GouttreatmentNot Availablewithdrawn
NCT05168683
Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tabletsother1completed
NCT04776161
Medication Adherence Patterns in Rheumatic Diseases: A Behavioral TrialNo drug interventionshealth_services_researchNot Availablecompleted
NCT06298071
A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.treatment1recruiting
NCT02477488
Optimal Administration of Allopurinol in Dialysis Patientsprevention4completed
NCT05927688
Assessment of Physician Consideration of ePRO's, From Patients With Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic AdjustmentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04808856
Treatment of Refractory Gout With ACTH or MethylprednisolonetreatmentNot Availableunknown_status
NCT00819585
A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)prevention2completed
NCT04839315
COVID-19 Vaccination in Rheumatic Disease PatientsNo drug interventionshealth_services_research0terminated
NCT03388515
A Study to Assess the Safety and Tolerability of SSS11 in Healthy Subjects.treatment1unknown_status
NCT02000232
Impact of Unapproved Drug Initiative on Colchicine UseNo drug interventionsNot AvailableNot Availablecompleted
NCT04052932
A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gouttreatment3completed
NCT02498652
Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjectstreatment2completed
NCT02741700
SToRytelling to Improve DiseasE Outcomes in GOut: The STRIDE-GO2 StudyNo drug interventionstreatmentNot Availablecompleted
NCT04125459
Assessing the Role of the NLRP3 Inflammasome in Intercritical GoutNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02716870
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk FactorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04987242
An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)treatment2completed
NCT03934099
A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemiatreatment2completed
NCT05665699
Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gouttreatment2recruiting
NCT03906006
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy SubjectsNo drug interventionstreatment1completed
NCT00856206
Review of Safety Using Rilonacept in Preventing Gout Exacerbations (RE-SURGE)prevention3completed
NCT05065606
Descriptive Analysis of Dual-energy Computed Tomography Exams of Adult Patients With GoutNo drug interventionsNot AvailableNot Availableunknown_status
NCT01642706
Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic TreatmentsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04459936
Urica Cor Intervention (URICORI) TrialNo drug interventionstreatmentNot Availablewithdrawn
NCT04897113
Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years OldNo drug interventionstreatmentNot Availableunknown_status
NCT02500641
Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gouttreatment4completed
NCT02219516
Mild, Moderate and Severe Renal Impairment Studybasic_science1completed
NCT04952896
Clinical Study of Magnetic Resonance Imaging and Deep Learning of Joint Synovial DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01459796
Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flarestreatment3terminated
NCT02330796
Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gouttreatment2completed
NCT02579096
CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostattreatment4completed
NCT03306758
The Efficiency and Safety of Sodium Bicarbonate on Uric Acid in Patients With Asymptomatic Hyperuricemia or GouttreatmentNot Availableunknown_status
NCT03274063
Gout Self-Monitoring Aiming to Reach TargetNo drug interventionstreatmentNot Availablecompleted
NCT00610363
Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flarestreatment2completed
NCT03038386
Diagnostic Value of DECT Scan Compared to Diagnostic Needle AspirationNo drug interventionsdiagnosticNot Availableunknown_status
NCT01336686
Safety and Efficacy Study of MBX-102 in Treatment of Hyperuricemia in Patients With Gouttreatment2completed
NCT04303039
Study to Investigate the Effects of Food on Relative Bioavailability of ABP-671 Tablets in Healthy SubjectsNo drug interventionstreatment1completed
NCT01830725
Purine Metabolism Enzyme SNP to Uric Acid ProductionNo drug interventionsNot AvailableNot Availablecompleted
NCT03272425
Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.treatment1completed
NCT05275348
Delivery of Enhance Fitness TrialNo drug interventionstreatmentNot Availableunknown_status
NCT01129648
Study to Evaluate sUA-Lowering Activity, Safety & PK Interaction of Oral BCX4208 & Allopurinol Admin. in Subjects w/Gouttreatment2completed
NCT03015948
A Single Dose Study of SHR4640 in Healthy Male Volunteersother1completed
NCT03635957
Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gouttreatment4completed
NCT01407874
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiencytreatment2completed
NCT01608620
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01808131
Lesinurad and Allopurinol Combination Extension Study in Gouttreatment3completed
NCT03994731
Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gouttreatment4completed
NCT01493531
Combining Lesinurad With Allopurinol in Inadequate Responderstreatment3completed
NCT02246673
RDEA3170 and Febuxostat Combination Study in Gout Subjectstreatment2completed
NCT05745727
A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid LevelsNo drug interventionstreatment1recruiting
NCT01654276
Effects of Hyperuricemia Reversal on Features of the Metabolic Syndrometreatment4completed
NCT03601260
The Percentage of Cases of Acute Treatment With Allopurinol in Gout PatientstreatmentNot Availableunknown_status
NCT04047394
A Study to Determine the Safety, Tolerability, PK and Preliminary PD of SSS11 in Chinese Healthy Adult Volunteerstreatment1unknown_status
NCT02578394
Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Studytreatment2 / 3completed
NCT04987294
Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Diseasetreatment2terminated
NCT02336594
RDEA3170 Bioavailability Studybasic_science1completed
NCT01363791
Meta-analyses of Fructose and Cardiometabolic RiskNo drug interventionsNot AvailableNot Availableunknown_status
NCT02187029
Efficacy, Safety And Tolerability Of PF-06743649 In Gout Subjects.No drug interventionstreatment1terminated
NCT01472692
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressuretreatment4completed
NCT00821392
Phase III Trial of Febuxostat in Korea Gout Patientstreatment3completed
NCT01808144
Lesinurad and Febuxostat Combination Extension Study in Gouttreatment3completed
NCT03650140
Pharmacokinetics and Pharmacodynamics of AnthocyaninsNo drug interventionsotherNot Availablecompleted
NCT05690204
Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.treatment2completed
NCT05127772
A Clinical Trial of HEC93077 in Chinese Healthy Subjects and HUA Patients With Single or Multiple DosingNo drug interventionstreatment1recruiting
NCT02648269
Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levelstreatment1completed
NCT01363869
Effects of Green Tea on Level of Serum Uric Acid in Healthy IndividualsNo drug interventionstreatmentNot Availablecompleted
NCT04070846
Mass Balance Study of [14C]LC350189 in Healthy Volunteerstreatment1completed
NCT01477346
Arthritis Research UK Gout Treatment Trial - Phase 2No drug interventionstreatmentNot Availablecompleted
NCT02139046
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gouttreatment3completed
NCT04066712
Renal PK Study of LC350189treatment1completed
NCT05499312
An Innovative Chinese Herbal Formula for the Treatment of GoutNo drug interventionstreatment2recruiting
NCT02083510
Apolipoprotein CIII Reduction Via Colchicinebasic_science0completed
NCT02608710
RDEA3170 PK/PD Studybasic_science1completed
NCT05256810
A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With GoutNo drug interventionstreatment1 / 2terminated
NCT01418781
CLinical Prediction Rule Score in VeteransNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00325195
Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gouttreatment3completed
NCT01736514
A Study to Evaluate Safety and Efficacy of Oral Febuxostat in Patients With Gouttreatment3completed
NCT04886050
Relative Bioavailability Study to Assess an LC350189 Tablet Compared to an LC350189 Capsule in Healthy Adultstreatment1completed
NCT05324423
To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gouttreatment1unknown_status
NCT01399008
Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patientstreatment2completed
NCT02230943
Rheumatology Informatics System for EffectivenessNo drug interventionsNot AvailableNot Availableunknown_status
NCT03211403
Multiple Doses Study of SHR4640 in Male Subjects With High Serum Uric Acid Levelother1completed
NCT03336203
The Impact of Urate-lowering Therapy on Kidney Function (IMPULsKF)treatment4unknown_status
NCT02128490
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairmenttreatment2completed
NCT02374164
Food Effect Study of Febuxostat XR in Healthy Participantstreatment1completed
NCT02462421
Pharmacogenetics of SGLT2 Inhibitorsbasic_science4terminated
NCT04511702
Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexatetreatment4completed
NCT02403687
Prospective Analgesic Compound Efficacy (PACE) StudyNot AvailableNot Availablecompleted
NCT04953533
Research and Development of a New Technology for Detection of Abnormal Excretion of Intestinal Uric Acid Involved in the Incidence of GoutNo drug interventionsNot AvailableNot Availableunknown_status
NCT00174954
Magnetic Resonance Imaging in Subjects With Gouty TophiNo drug interventionsNot AvailableNot Availablecompleted
NCT01927198
RDEA3170 Monotherapy in Subjects With Gouttreatment2completed
NCT02464605
Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levelstreatment1completed
NCT01818505
The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT05607797
Genetic of Chronic Kidney Disease and Gout in New CaledoniaNo drug interventionsotherNot Availablerecruiting
NCT02063997
Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patientstreatment2completed
NCT00506883
MPC-004 for the Treatment of an Acute Gout Flaretreatment3completed
NCT03131583
The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gouttreatment1completed
NCT02471261
Elastography as Gouty Arthropathy Outcome (EGO)No drug interventionsNot AvailableNot Availablecompleted
NCT03840928
PatientSpot Formerly Known as ArthritisPowerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04695028
CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related ArthropathiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04804111
Study of of URC102 to Assess the Efficacy and Safety in Gout Patientstreatment2completed
NCT02113111
Effects of Fasting on Self EfficacyNo drug interventionsNot AvailableNot Availablecompleted
NCT00584311
MRI and Ultrasound Findings in Patients With Gout and Normal Plain RadiographsNo drug interventionsdiagnosticNot Availablecompleted
NCT05546593
Prevalence of Abnormalities in Ultrasonography of Joint and Tendons in Patients With GoutNo drug interventionsNot AvailableNot Availablerecruiting
NCT04072471
Post-Authorisation Safety Study of LesinuradNot AvailableNot Availablewithdrawn
NCT04040907
The the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of XNW3009 in Health SubjectNo drug interventionstreatment1completed
NCT01151709
Assessment of Primary Care Providers' Knowledge and Beliefs Regarding Gout ManagementNo drug interventionsNot AvailableNot Availablecompleted
NCT00174915
Phase 3, Febuxostat, Allopurinol and Placebo-Controlled Study in Gout Subjects.treatment3completed
NCT02855437
Novel Methods for Ascertainment of Gout Flares -A Pilot StudyNo drug interventionsotherNot Availablecompleted
NCT01563432
Clinical Study to Evaluate the Pharmacokinetic Characteristics Between TMX-67 and Feburic® in Healthy Volunteerstreatment1completed
NCT04956432
A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gouttreatment3active_not_recruiting
NCT01872832
Single and Multiple Dose Study in Japanese SubjectsNo drug interventionstreatment1completed
NCT02702375
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT06056570
Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemiatreatment1 / 2recruiting
NCT00738842
Uric Acid Study in Healthy Male Volunteersbasic_science1completed
NCT02950142
Evidence-based Laboratory Test Order Sets in Primary CareNo drug interventionsdiagnosticNot Availablecompleted
NCT03226899
A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairmenttreatment4terminated
NCT01529099
Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEMNo drug interventionstreatment4completed
NCT00175006
Validation Study of Physical Measurement of TophiNo drug interventionsNot AvailableNot Availablecompleted
NCT05109936
Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed Administrationtreatment3not_yet_recruiting
NCT06258213
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy VolunteersNo drug interventionsother1recruiting
NCT00995618
Study of Tranilast Alone or in Combination With Febuxostat in Patients With Hyperuricemiatreatment2completed
NCT02287818
A Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Gouttreatment2completed
NCT06187519
UR+AIMS Gout Wearable Skin Uric Acid Monitor StudyNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01881919
Effect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over TrialNo drug interventionsbasic_science0completed
NCT00175019
Allopurinol Versus Febuxostat in Subjects Completing the Phase 3 Trials C02-009 or C02-010treatment3completed
NCT02279641
RDEA3170 and Allopurinol Combination Study in Gout Subjectsbasic_science1completed
NCT00174941
Long-Term Safety of Febuxostat in Subjects With Gout.treatment2completed
NCT03162341
Study of the Correlation Between UltraSonography and Dual-Energy Computed Tomography Assessment of Urate DepositNo drug interventionsdiagnosticNot Availablecompleted
NCT01021241
Safety and Efficacy Study of Intravenous Uricase-PEG 20treatment1unknown_status
NCT04213534
The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients:A Prospective Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04139824
The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adultstreatment1completed
NCT01685424
Etoricoxib Prescribing Patterns and Adverse Events of Interest in Primary Care in the United Kingdom (MK-0663-162 AM1)Not AvailableNot Availablecompleted
NCT04938024
Hmong Microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C)No drug interventionstreatmentNot Availablecompleted
NCT04040816
Placebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAP-001 in Gout PatientsNo drug interventionstreatment2completed
NCT02598596
Tolerization Reduces Intolerance to Pegloticase and Prolongs the Urate Lowering Effectother2completed
NCT01510158
Combining Lesinurad With Allopurinol in Inadequate Responderstreatment3completed
NCT02252835
Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gouttreatment2completed
NCT04829435
Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)treatment1completed
NCT03214263
Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02790463
Virtual Gout ClinicNo drug interventionstreatmentNot Availablecompleted
NCT03345186
A Nurse Led Patient Management Programme to Improve Outcomes in GoutNo drug interventionsotherNot Availablecompleted
NCT04812886
Epidemiology of Gout in French PolynesiaNo drug interventionsotherNot Availablecompleted
NCT01701622
The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot StudytreatmentNot Availableterminated
NCT06211322
The Remote Monitoring of Gout Feasibility StudyNo drug interventionshealth_services_researchNot Availablerecruiting
NCT04199325
Probiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical TrialtreatmentNot Availablerecruiting
NCT01391325
Allopurinol Outcome Studytreatment4completed
NCT05473325
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04966325
Thorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Female Subjectstreatment0completed
NCT00430248
Efficacy and Safety of Oral Febuxostat in Participants With Gouttreatment3completed
NCT05309057
Network Meta-analysis of Intermittent Fasting and Cardiometabolic RiskNo drug interventionsNot AvailableNot Availableunknown_status
NCT00111657
Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gouttreatment2completed
NCT02557126
Study of URC102 to Assess the Safety and Efficacy in Gout PatientsNo drug interventionstreatment2completed
NCT01994226
Colchicine Or Naproxen Treatment for ACute gouTtreatment4completed
NCT03569020
The Diet Gout TrialNo drug interventionstreatmentNot Availablecompleted
NCT03291782
D-0120 Safety and PK/PD, Food Effect Study in Healthy VolunteersNo drug interventionstreatment1completed
NCT01112982
An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.diagnostic4completed
NCT04060173
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671No drug interventionstreatment1completed
NCT01312727
Hereditary Tubulointerstitial NephritisNo drug interventionsscreeningNot Availablecompleted
NCT00985127
Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With Gouttreatment2completed
NCT04960527
Acute Effects of Tart Cherry on Uric Acid and Biomarkers of CVD Risk in Healthy IndividualsNo drug interventionspreventionNot Availablecompleted
NCT04853160
Drug Use Study of Febuxostat After Recent Changes in the Prescribing InformationNo drug interventionsNot AvailableNot Availablecompleted
NCT02393560
DECT Study in Allopurinol-Treated Gout PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04224662
A Pilot Study to Explore the Role of Gut Flora in GoutNo drug interventionsNot AvailableNot Availableunknown_status
NCT04746989
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs AllopurinolNot AvailableNot Availableactive_not_recruiting
NCT05007392
A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gouttreatment3completed
NCT00102440
Febuxostat Versus Allopurinol Control Trial in Subjects With Gouttreatment3completed
NCT00174967
Dose-Response, Safety and Efficacy of Febuxostat in Subjects With Goutdiagnostic2completed
NCT05815901
A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patientstreatment3recruiting
NCT05006001
Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout PatientsNot AvailableNot Availableactive_not_recruiting
NCT04130204
Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS)treatment2completed
NCT06189404
Effect of Tigulixostat on the Pharmacokinetics of Theophyllinebasic_science1completed
NCT01884272
NSAID Drug Interaction Studybasic_science1completed
NCT02082769
Safety and Efficacy of Oral Febuxostat in Subjects With Gouttreatment3completed
NCT01650246
Open-Label Lesinurad Monotherapy Extension Study in Gouttreatment3completed
NCT01361646
Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of LC350189treatment1completed
NCT02903446
Denosumab In Addition To Intense Urate-Lowering Therapy for Bone Erosionstreatment2completed
NCT02290210
Phase 2 Study of URC102 to Assess the Efficacy and Safety in Gout PatientsNo drug interventionstreatment2completed
NCT06235710
Prevalence of Musculoskeletal Complaints in Nursing Home ResidentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00080210
A Study of Persons With Gout Who Do Not Respond to or Are Allergic to Conventional Therapytreatment2completed
NCT01549210
Italian Observational Study Assessing the Impact of Gout on Patients Disability and Quality of LifeNo drug interventionsNot AvailableNot Availablecompleted
NCT05454423
Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With HyperuricemiaNo drug interventionstreatmentNot Availableunknown_status
NCT01001338
Allopurinol Combination Studytreatment2completed
NCT00958438
PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2)treatment3completed
NCT04638543
A Study to Assess the Efficacy, Safety, and Pharmacokinetics of ABP-671 in Patients With Gout or HyperuricemiaNo drug interventionstreatment2completed
NCT06068478
A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty ArthritisNo drug interventionstreatment3recruiting
NCT04462666
Oral Huzhang Granules for Acute Gouty Arthritistreatment2unknown_status
NCT01867840
Role of ASICs in Human Inflammatory PainNo drug interventionsNot AvailableNot Availableunknown_status
NCT05332795
The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.treatmentNot Availablecompleted
NCT01626235
AMPED Outcomes Registry of Post-ED Pain ManagementNo drug interventionsNot AvailableNot Availablecompleted
NCT05964946
Real-life Study of the Characteristics of Patients Treated With Ilaris® (Canakinumab) for Gouty Arthritis in FranceNo drug interventionsNot AvailableNot Availablecompleted
NCT00927810
Long Term Study of Canakinumab (ACZ885) in Patients With Gouttreatment2completed
NCT01362608
Safety & Efficacy of Canakinumab (ACZ885) in Patients With Frequent Flares for Whom Nonsterodial Anti-Inflammatory Drug (NSAIDs) and/ or Colchicine Are Contraindicated, Not Tolerated or Ineffectivetreatment3terminated