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Displaying results 931 - 940 of 8695 in total
  1. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function. … By blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  2. Drug

    Letetresgene autoleucel

    go.drugbank.com/drugs/DB17233
    Investigational

    Synonyms: NY-ESO-1 T cell receptor
  3. Drug

    Anti-CD4 CAR T-cell therapy

    go.drugbank.com/drugs/DB17281
    Experimental

    Synonyms: chimeric antigen receptor directed against the target protein CD4 lentivirally transfected T cells
  4. Target

    Mas-related G protein-coupled receptor member X2

    go.drugbank.com/bio_entities/BE0018408
    TargetHumans

    Mast cell-specific G protein-coupled receptor for basic secretagogues, which regulates mast cell degranulation and itch-related hypersensitivity reactions (PubMed:22069323, PubMed:25517090, PubMed:28288109 … Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37

    Polypeptides: Mas-related G protein-coupled receptor member X2Function: C-C chemokine receptor activity
  5. Drug

    Solrikitug

    go.drugbank.com/drugs/DB19301
    Investigational

    Solrikitug is under investigation in clinical trial NCT06496607 (A Study to Evaluate Solriktug in Adult Participants With Asthma).

    Synonyms: Immunoglobulin G1-kappa, anti-[Homo sapiens CRLF2 (cytokine receptor like factor 2,TSLP, thymic stromal lymphopoietin)], humanized monoclonal antibody
  6. Drug

    Japanese encephalitis vaccine (live, attenuated)

    go.drugbank.com/drugs/DB16577
    Investigational

    Products: POWDER AND DILUENT FOR SUSPENSION FOR INJECTION
  7. Drug

    Montmorillonite

    go.drugbank.com/drugs/DB13654
    Investigational

    Products: DIMECTAL Powder for Oral Suspension 3g, Smecta Strawberry Flavour Powder for Oral Suspension 3g
  8. Drug

    Cefadroxil

    go.drugbank.com/drugs/DB01140
    ApprovedInvestigationalVet approvedWithdrawn

    Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: ANPRODROXIL GRANULES FOR ORAL SUSPENSION 125mg/5ml, Biodroxil 125 mg/5 ml - Pulver zur Herstellung einer Suspension zum Einnehmen
  9. Drug

    Bilberry

    go.drugbank.com/drugs/DB14235
    ApprovedWithdrawn

    Synonyms: Myrtilli fructus recens (vaccinium myrtillus l.)Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  10. Pathway

    Minaprine Serotonin receptor Antidepressant Action Pathway

    smpdb.ca/view/SMP0126747
    Drug action

    MAO A inhibition is thought to be more relevant to antidepressant activity than the inhibition caused by MAO B. Selective MAO B inhibitors have no antidepressant effects. … Minaprine acts on many targets in the neurons. Firstly, this drug binds as an antagonist to the serotonin type 2 receptors (C, B, and C).

    Drugs: Pyridoxal phosphate · Tryptophan · Sapropterin · Minaprine · Calcium · Iron +2 more
    Enzymes: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C