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Displaying results 9441 - 9450 of 10000 in total
  1. Drug

    Idazoxan

    go.drugbank.com/drugs/DB12551
    Investigational

    Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.

  2. Drug

    Icaritin

    go.drugbank.com/drugs/DB12672
    Investigational

    Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).

  3. Drug

    Ninvosudil

    go.drugbank.com/drugs/DB08756
    Investigational

    Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.

    Synonyms: (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
  4. Drug

    Briciclib

    go.drugbank.com/drugs/DB12004
    Investigational

    Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and Acute Lymphocytic Leukemia.

  5. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF). … As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.

  6. Drug

    Mephenytoin

    go.drugbank.com/drugs/DB00532
    ApprovedWithdrawn

    Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. … Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures.

  7. Drug

    Elsulfavirine

    go.drugbank.com/drugs/DB14929
    Investigational

    Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food

  8. Drug

    DTX-101

    go.drugbank.com/drugs/DB17699
    Investigational

    DTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene.

  9. Drug

    Macozinone

    go.drugbank.com/drugs/DB14821
    Investigational

    Macozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).

  10. Drug

    JQ1

    go.drugbank.com/drugs/DB17021
    Experimental

    First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]

    Synonyms: (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate