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Displaying results 941 - 950 of 10000 in total
  1. Target

    Non-secretory ribonuclease

    go.drugbank.com/bio_entities/BE0001306
    TargetHumans

    This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells.

    Polypeptides: Non-secretory ribonuclease
  2. Target

    Non-heme chloroperoxidase

    go.drugbank.com/bio_entities/BE0003176
    TargetStreptomyces aureofaciens

    Polypeptides: Non-heme chloroperoxidase
  3. Target

    Non-lysosomal glucosylceramidase

    go.drugbank.com/bio_entities/BE0020281
    TargetHumans

    Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramides/GlcCers (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) to free glucose and ceramides (such as N-acylsphing-4

    Polypeptides: Non-lysosomal glucosylceramidaseSynonyms: Non-lysosomal glycosylceramidase, Non-lysosomal galactosylceramidase
  4. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.

  5. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    Mixtures: Extra Once A Day, Maximum Once A Day
  6. Drug

    Nadolol

    go.drugbank.com/drugs/DB01203
    ApprovedInvestigational

    [L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and

    Categories: Beta Blocking Agents, Non-Selective, Beta Blocking Agents, Non-Selective, and Thiazides
  7. Drug

    Turoctocog alfa

    go.drugbank.com/drugs/DB09109
    Approved

    [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] … Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally

  8. Drug

    Enoximone

    go.drugbank.com/drugs/DB04880
    ApprovedInvestigationalWithdrawn

    Trials were halted in the U.S., but the drug is used in various countries. … Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption.

  9. Drug

    Ebola Zaire vaccine (live, attenuated)

    go.drugbank.com/drugs/DB15595
    ApprovedInvestigational

    These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal and external bleeding. … [L10854] Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease.

  10. Drug

    Metolazone

    go.drugbank.com/drugs/DB00524
    ApprovedInvestigational

    A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.

    Categories: Non Potassium Sparing Diuretics, Low-Ceiling Diuretics, Excl. Thiazides