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Displaying results 941 - 950 of 10000 in total
  1. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: PEMETREXED MASTERS® 500 MG POLVO LIOFILIZADO ESTÉRIL PARA RECONSTITUIR A SOLUCION INYECTABLE., NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  2. Drug

    Linezolid

    go.drugbank.com/drugs/DB00601
    ApprovedInvestigational

    [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor. … Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria.

    Synonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-Ring
  3. Target

    Probable arabinosyltransferase A

    go.drugbank.com/bio_entities/BE0000034
    TargetMycobacterium tuberculosis

    Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.

    Polypeptides: Probable arabinosyltransferase A
  4. Target

    Aurora kinase A

    go.drugbank.com/bio_entities/BE0000991
    TargetHumans

    Plays a role in microtubule remodeling during neurite extension (PubMed:19668197). … Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome

    Polypeptides: Aurora kinase ASynonyms: Serine/threonine-protein kinase aurora-A
  5. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001362
    TargetChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  6. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001810
    TargetEnzymeThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Beta-glucosidase A
  7. Target

    Complement C4-A

    go.drugbank.com/bio_entities/BE0004685
    TargetHumans

    Precursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that

    Polypeptides: Complement C4-A
  8. Target

    Pepsin A-5

    go.drugbank.com/bio_entities/BE0009737
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-5
  9. Target

    Pepsin A-4

    go.drugbank.com/bio_entities/BE0012524
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-4
  10. Target

    Pepsin A-3

    go.drugbank.com/bio_entities/BE0012527
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-3