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Fingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigational[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. … Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects.
Categories: Sphingosine 1-phosphate Receptor Modulator, Sphingosine 1 Phosphate Receptor ModulatorsProducts: DROPTON®, GENBIEMOD®Vemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigationalAfter approval, Roche in collaboration with Genentech launched a broad development program. [L1012] … Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E.[A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MGMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigationalMirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. … Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its
Categories: Adrenergic beta-3 Receptor Agonists, P-glycoprotein inhibitorsProducts: MYRBETRIC® 50 MG TABLETAS DE LIBERACION PROLONGADA, MYRBETRIC® 25 MG TABLETAS DE LIBERACION PROLONGADACanagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalCanagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … 2 diabetes mellitus [L5897], [FDA label].
Mixtures: VOKANAMET ® TM_TABLETAS RECUBIERTAS 150/1000 MGCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsIodamide
go.drugbank.com/drugs/DB08948ApprovedWithdrawnIodamide is a contrast medium molecule that is no longer marketed in the United States.
Categories: X-Ray Contrast Media, Iodinated, Compounds used in a research, industrial, or household settingIndoramin
go.drugbank.com/drugs/DB08950ApprovedWithdrawnIt is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. … Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese.
Categories: Adrenergic alpha-1 Receptor Antagonists, Peripheral alpha-1 blockersHydroxydione
go.drugbank.com/drugs/DB08956ApprovedWithdrawnHydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.
Dimetotiazine
go.drugbank.com/drugs/DB08967ApprovedDimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.
Categories: Heterocyclic Compounds, 3-RingFominoben
go.drugbank.com/drugs/DB08968ApprovedWithdrawnFominoben is an antitussive agent.
Categories: Heterocyclic Compounds, 1-RingFlubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Categories: Heterocyclic Compounds, 2-RingSynonyms: methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate, (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester