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Peptidoglycan recognition protein 3
go.drugbank.com/bio_entities/BE0003077TargetHumansPattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to...
Synonyms: PGRP-I-alpha, Peptidoglycan recognition protein I-alphaUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG Therapeutics in 2012. … CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.
Categories: Leukemia, Lymphocytic, Chronic, B-Cell, drug therapyCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. … It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Strontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnAvailable for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts.
Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETCategories: Heterocyclic Compounds, 1-RingLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.
Mixtures: Van-losartan-hctz, Van-losartan-hctzCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin II Type 1 Receptor BlockersRetinol-binding protein 1
go.drugbank.com/bio_entities/BE0000301TargetCarrierHumansCytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518). Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubM...
Synonyms: CRBP-I, Cellular retinol-binding protein IXylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnNevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes. … The dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar in living things. The levorotary form, L-xylose, can refer to the form that is synthesized.
Synonyms: D-Xylose, aldehydo-D-xyloseCisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalIt was the first member of its class, which now also includes carboplatin and oxaliplatin. … Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: CIS-DIAMMINEDICHLOROPLATINUM II, cis-diamminedichloroplatinum(II)Cefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalIn most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis). … Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria.
Mixtures: SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET, XENLID IMCategories: Heterocyclic Compounds, 2-RingPolysilicone-15
go.drugbank.com/drugs/DB11271ApprovedIt is the first polymeric UVB filer consisting of chromophores attached to a silicone backbone [L2796, L2797, L2799, F87, F88, F89]. … The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium polarity and insoluble in water [L2796, L2797, L2799, F87, F88, F89].