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Displaying results 951 - 960 of 10000 in total
  1. Pathway

    Dienogest Action Pathway

    smpdb.ca/view/SMP0126541
    Drug action

    Dienogest is a semisynthetic progestogen derived from 19-nortestosterone and has antiandrogenic properties. This drug is used as a contraceptive or to treat endometriosis alone or combined with ethinylestradiol. Dienogest acts by binding...

    Drugs: NADH · ATP · Progesterone · Testosterone · Estrone · Potassium cation +9 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  2. Pathway

    Gi Adrenergic Smooth Muscle Contraction

    smpdb.ca/view/SMP0126894
    Physiological

    The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  3. Pathway

    Levonorgestrel Action Pathway

    smpdb.ca/view/SMP0125332
    Drug action

    Levonorgestrel (LNG) is a progestin (synthetic progestogen) found in contraceptives (birth control) that are taken orally, in subdermal implants or in intrauterine devices (IUD). Oral contraceptives and IUDs have a low dose, while emerge...

    Drugs: NADH · ATP · Levonorgestrel · Progesterone · Testosterone · Estrone +9 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  4. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. … make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: TAMLET-S, LEPREZIL SL
  5. Drug

    Pozanicline

    go.drugbank.com/drugs/DB05458
    Investigational

    Neuronal nicotinic acetylcholine receptors (nAChRs) modulate the release of several important neurotransmitters, such as acetylcholine and dopamine. … In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR subtypes.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Pathway

    Formoterol Action Pathway

    smpdb.ca/view/SMP0126086
    Drug action

    Formoterol is a long acting beta-2 adrenergic receptor agonist that is used as a bronchodilator and to manage asthma and COPD. It can be used as well for prophylaxis against exercise induced bronchospasm. This drug is inhaled and can be ...

    Drugs: ATP · Formoterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  7. Pathway

    Arformoterol Action Pathway

    smpdb.ca/view/SMP0126088
    Drug action

    Arformoterol is a beta-2 adrenergic receptor agonist that is used as a bronchodilator to treat COPD and chronic bronchitis. It accomplishes this by upon inhalation of the drug by relaxing smooth muscles in the airways to improve breathin...

    Drugs: ATP · Arformoterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  8. Pathway

    Olodaterol Action Pathway

    smpdb.ca/view/SMP0126091
    Drug action

    Olodaterol is a beta-2 adrenergic agonist that is long acting. It is used for the management of chronic bronchitis and COPD, but not asthma. It accomplishes this by mediating smooth muscle relaxation and bronchodilator via L-type calcium...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Olodaterol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  9. Pathway

    Terbutaline Action Pathway

    smpdb.ca/view/SMP0126093
    Drug action

    Terbutaline is a beta-2 adrenergic receptor agonist that is used primarily as a bronchodilator. It can be found under the brand name Bricanyl and is an inhaled drug with a short duration. It is used for the prevention and reversal of bro...

    Drugs: ATP · Terbutaline · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  10. Pathway

    Procaterol Action Pathway

    smpdb.ca/view/SMP0126094
    Drug action

    Procaterol is a beta-2 adrenergic agonist that is used as a bronchodilator. It is a long acting and potent drug that can be taken orally or through inhalation for the treatment of asthma and COPD. The purpose of this drug is to increase ...

    Drugs: ATP · Potassium cation · Procaterol · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12