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Diazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIt is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential
Mixtures: Gabavale-5Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesIncrease in Intracranial Pressure (ICP)
go.drugbank.com/conditions/DBCOND0113421Synonyms: Increase in Intracranial Pressure (ICP)Leydig Cell Failure in Adult
go.drugbank.com/conditions/DBCOND0081825Drugs: MesteroloneSynonyms: Leydig Cell Failure in Adult, Leydig cell failure in adult (disorder)Burning sensation in the mouth
go.drugbank.com/conditions/DBCOND0102063Drugs: Benzoic acidSynonyms: Discomfort in mouth, Burning sensation in the mouthUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawnUrokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. … [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Products: UROKINASE KGCC INJ. 250000 IU FLAKON, 1 ADET, UROKINASE KGCC INJ. 500000 IU FLAKON, 1 ADETDeficiencies in enzymes of the urea cycle
go.drugbank.com/conditions/DBCOND0023710Drugs: Phenylbutyric acidSynonyms: Deficiencies in enzymes of the urea cycleRepaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalRepaglinide is extensively metabolized in the liver and excreted in bile. Repaglinide metabolites do not possess appreciable hypoglycemic activity. … Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine.
Mixtures: REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET, REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesAcyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
go.drugbank.com/bio_entities/BE0002505TargetHelicobacter pylori (strain ATCC 700392 / 26695)Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Polypeptides: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferaseFunction: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activityAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. … [A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation.
Categories: Metabolic Side Effects of Drugs and Substances, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuranFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigationalThe manufacturer and the FDA advise health professionals to limit the use of febuxostat to second-line therapy in patients who have inadequate response or intolerance to allopurinol, and to avoid the use … [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid