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Displaying results 961 - 970 of 10000 in total
  1. Target

    Chitinase A

    go.drugbank.com/bio_entities/BE0001649
    TargetSerratia marcescens

    Polypeptides: Chitinase A
  2. Target

    Gyrase A

    go.drugbank.com/bio_entities/BE0008384
    TargetMycobacterium tuberculosis

    Polypeptides: Gyrase A
  3. Target

    Cyclin A

    go.drugbank.com/bio_entities/BE0009669
    Target

  4. Target

    Proenkephalin-A

    go.drugbank.com/bio_entities/BE0010659
    TargetHumans

    They play a role in a number of physiologic functions, including pain perception and responses to stress

    Polypeptides: Proenkephalin-A
  5. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of … VIII, the essential human blood clotting protein that is impaired in Hemophilia A.

    Synonyms: B-domain deleted recombinant factor VIII, Human factor VIII, recombinant B-domain deletedProducts: REFACTO AF 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUC FLAKON, 1 ADET, REFACTO AF 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADET
  6. Drug

    Hydroxyethyl Starch

    go.drugbank.com/drugs/DB09106
    ApprovedInvestigational

    HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.

    Mixtures: Hydroxyethyl Starch in Sodium Chloride, PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 1000 ML SETSIZCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Secukinumab

    go.drugbank.com/drugs/DB09029
    ApprovedInvestigational

    Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque … [A249840] Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015).

    Products: COSENTYX SOLUTION FOR INJECTION IN PREFILLED SYRINGE 150MG/ML, Fraizeron 150mg/ml solution for injection in pre-filled pen
  8. Target

    Apolipoprotein(a)

    go.drugbank.com/bio_entities/BE0001283
    TargetHumans

    Lp(a) may be a ligand for megalin/Gp 330 … Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.

    Polypeptides: Apolipoprotein(a)Synonyms: Lp(a), Apo(a)
  9. Target

    Exotoxin A

    go.drugbank.com/bio_entities/BE0001869
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis (PubMed:18276581, PubMed:2170123). Ha...

    Polypeptides: Exotoxin A
  10. Target

    Endoglucanase A

    go.drugbank.com/bio_entities/BE0002017
    TargetClostridium thermocellum

    This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Polypeptides: Endoglucanase ASynonyms: Cellulase A