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Gastric intrinsic factor
go.drugbank.com/drugs/DB09349ApprovedIntrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later … Intrinsic factor is not currently available in any FDA or Health Canada approved products.
Mixtures: EnLyte Extra-LNInulin
go.drugbank.com/drugs/DB00638ApprovedInvestigationalNutraceuticalIt has been used in physiologic investigation for determination of the rate of glomerular function. … A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
Categories: Compounds used in a research, industrial, or household setting, Tests for Renal Function and Ureteral InjuriesGrazoprevir
go.drugbank.com/drugs/DB11575Approvedin combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593]. … in the NS5A protein and previous treatment failure with [DB00811], [DB00008], [DB00022], or other NS3/4A inhibitors like [DB08873], [DB06290], or [DB05521] [FDA Label].
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsDabocemagene autoficel
go.drugbank.com/drugs/DB17878InvestigationalDeveloped by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797] … Dabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen.
Synonyms: TRANSDUCED HUMAN AUTOLOGOUS DYSTROPHIC EPIDERMOLYSIS BULLOSA DERMAL FIBROBLAST CELL FCX-007 INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND 3'-LTR/PO, THE CONTROL OF A HUMAN CYTOMEGALOVIRUS (CMV) PROMOPibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalIn clinical trials, this combination therapy achieved SVR12 rate, or undetectable Hepatitis C for twelve or more weeks after the end of treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 [L940] … These resistance-associated amino acid substitutions included Q30D/deletion, Y93D/H/N or H58D +Y93H in genotype 1a replicons, F28S + M31I or P29S + K30G in genotype 2a replicons, and Y93H in genotype 3a
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalThese biochemical changes result in a reduced tendency for self-association resulting in dissolution to a dimer and then to a monomer that is absorbed more rapidly after subcutaneous injection compared … If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening
Mixtures: Humalog Mix 25 (pen), Humalog Mix 25 (pen)Categories: Drugs Used in Diabetes, Insulins and Analogues for Injection, Fast-ActingAlginic acid
go.drugbank.com/drugs/DB13518ApprovedInvestigationalWithdrawnAvailable in different types of salt, alginic acid has been used in a variety of uses in food, cosmetics and pharmaceu-tical products for over 100 years [A32961]. … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (_Phacophycae_) via alkaline extraction.
Mixtures: MILACID® SACHET POR 10ML SABOR MENTA, GAVISCON BRUCIORE E INDIGESTIONECategories: Compounds used in a research, industrial, or household setting, Drugs for Acid Related DisordersSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalEnspryng®, a satralizumab formulation developed by Chugai Pharmaceutical and Roche,[L15536] is uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors … Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive patients with NMOSD.
Products: ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML, ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringeNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedIt is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.
Mixtures: Troxyca ER, Troxyca ERCategories: Heterocyclic Compounds with 4 or More Rings, Drugs Used in Alcohol DependenceCalcium lactate
go.drugbank.com/drugs/DB13231ApprovedVet approvedCalcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). … Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Mixtures: Pro Enz Tab, Calcium Lactate Et Magnesium SulfateSynonyms: Hemicalcium L-lactate