Search
Glisoxepide
go.drugbank.com/drugs/DB01289InvestigationalGlisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) and
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesPirbuterol
go.drugbank.com/drugs/DB01291ApprovedWithdrawnPirbuterol is a beta-2 adrenergic bronchodilator. … in a concentration between 10-50%.
Categories: Compounds used in a research, industrial, or household setting, Adrenergic beta-2 Receptor AgonistsBevantolol
go.drugbank.com/drugs/DB01295InvestigationalBevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. … Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol, 1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-olPractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol, N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamideSulfacytine
go.drugbank.com/drugs/DB01298ApprovedSulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. … Sulfacytine is a competitive inhibitor of the enzyme dihydropteroate synthetase.
Synonyms: 1-ethyl-N-sulfanilylcytosine, 1-ethyl N4-sulfanilylcytosinCefazolin
go.drugbank.com/drugs/DB01327ApprovedInvestigationalA semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Mixtures: CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET, CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingCilazapril
go.drugbank.com/drugs/DB01340ApprovedInvestigationalIt is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States.
Mixtures: INHIBACE PLUS 5 MG TABLET, 28 ADET, Inhibace plus 5 mg/12,5 mg - FilmtablettenCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingForasartan
go.drugbank.com/drugs/DB01342ExperimentalAs angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Heterocyclic Compounds, 1-Ring, Angiotensin II Type 1 Receptor BlockersPotassium cation
go.drugbank.com/drugs/DB01345ApprovedThe cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. … The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.
Mixtures: Telom-X-geneSynonyms: potassium(1+), potassium(1+) ionSpirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalSpirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart fa...