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Reserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnAn alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine.[L43942]
Mixtures: Renese-RCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: IMPOFIN-Z®, AZYDROP®15 MG/GAdapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigationalOn December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.[L12873] … [A193518] Differin®, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution.
Mixtures: GLENPALENE-C® GEL, Clindap-TSynonyms: 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acidMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalIt is used as a vasoconstrictor agent in the treatment of hypotension.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AgonistsSynonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamideTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamideMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalMoxifloxacin is a synthetic fluoroquinolone antibiotic agent.
Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingNelfinavir
go.drugbank.com/drugs/DB00220ApprovedInvestigationalNelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsIsoetharine
go.drugbank.com/drugs/DB00221ApprovedIsoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.[A330]
Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigational2 diabetes mellitus. … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular
Mixtures: AMARYL®M 1 MG/ 500 MG, AMARYL®M 4 MG/ 1000 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesDiflorasone
go.drugbank.com/drugs/DB00223ApprovedDiflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
International brands: Florone EProducts: Psorcon E, ApexiCon E