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Displaying results 971 - 980 of 10000 in total
  1. Drug

    Magnesium hydroxide

    go.drugbank.com/drugs/DB09104
    ApprovedInvestigational

    Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).

    Mixtures: Neo Tigol Tab, DYNA-U TABLETProducts: Milk Of Magnesia 7% To 8.5%, Dermagran II Ointment 0.25%
  2. Drug

    ssCART-19 cells

    go.drugbank.com/drugs/DB18653
    Investigational

    ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).

    Synonyms: autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19 cells)
  3. Target

    Dihydropteroate synthase type-1

    go.drugbank.com/bio_entities/BE0004657
    TargetEscherichia coli

    The type II enzyme is stable whereas type I DHPS loses its activity rapidly.

    Synonyms: Dihydropteroate synthase type I, Dihydropteroate pyrophosphorylase type I
  4. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. … [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough.

    Mixtures: Van-losartan-hctz, Van-losartan-hctzCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin II Type 1 Receptor Blockers
  5. Drug

    Bismuth subgallate

    go.drugbank.com/drugs/DB13909
    Approved

    Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. … Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter

    Mixtures: KORTOS KREM, 30 G
  6. Target

    Thioesterase 1/protease 1/lysophospholipase L1

    go.drugbank.com/bio_entities/BE0002014
    TargetEscherichia coli (strain K12)

    TesA is a multifunctional esterase that can act as a thioesterase, lysophospholipase and protease (PubMed:10423542, PubMed:1864840, PubMed:238979, PubMed:4554913, PubMed:4945109, PubMed:791643, PubMed:

    Synonyms: Thioesterase I/protease I, TEP-I
  7. Drug

    Pramipexole

    go.drugbank.com/drugs/DB00413
    ApprovedInvestigational

    RLS is a sleep-related disorder characterized by unpleasant sensations in the lower extremities, often accompanied by an uncontrollable urge to move the legs [A176876]. … It was first approved by the FDA in 1997 [L5882].

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (S)-N  6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
  8. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol _Zn_ [L2098]. … It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division.

    Mixtures: O-Cal Prenatal Vitamin, O-Cal FA multivitaminProducts: ZINCO-K 15MG/5 ML 28 KASIK SURUP, ZINCO-K 15MG/5 ML KASIK SURUP, 20 ADET
  9. Target

    Dynamin-1

    go.drugbank.com/bio_entities/BE0013996
    TargetHumans

    Depending on the curvature imposed on the tubules, membrane detachment from the helical polymer upon GTP hydrolysis can cause spontaneous hemifission followed by complete fission (PubMed:19084269). … Mediates rapid endocytosis (RE), a Ca(2+)-dependent and clathrin- and K(+)-independent process in chromaffin cells (By similarity).

    Synonyms: Dynamin I
  10. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitorsSynonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine