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Creatine Kinases
go.drugbank.com/bio_entities/BE0009627EnzymeTargetHumansReversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energ...
Synonyms: S-MtCKPolypeptides: Creatine kinase S-type, mitochondrialQuinoprotein glucose dehydrogenase B
go.drugbank.com/bio_entities/BE0001728TargetEnzymeAcinetobacter calcoaceticusOxidizes glucose to gluconolactone.
Synonyms: s-GDHGabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.
Mixtures: Innoprax-5, GAVINDO NSynonyms: 1-(Aminomethyl)cyclohexaneacetic acidAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedThe primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near the skin surface [A27159]. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.
Mixtures: KURSEPT %19 + %1 KREM (30 G), PERS-MANT %19 + %2 JEL (30 G)Products: Charm-Tex Deodorant, Lemon Ginger Tea DeodorantIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalIodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. … As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see
Salts: Sodium iodide I-131Synonyms: 131 I, 131-IPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Mixtures: Ryna -12 S, Stona-SCategories: Adrenergic alpha-1 Receptor Agonists, Monoamine Oxidase A SubstratesGlutamate mutase sigma subunit
go.drugbank.com/bio_entities/BE0001771TargetClostridium tetanomorphumCatalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
Synonyms: Glutamate mutase S chainAnamorsin
go.drugbank.com/bio_entities/BE0015312TargetHumansComponent of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. … Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2.
Synonyms: Fe-S cluster assembly protein DRE2 homologCytochrome P450 2C19
go.drugbank.com/bio_entities/BE0003536EnzymeTargetHumansOxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol (PubMed:11950794). … Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine
Synonyms: (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenaseNetarsudil
go.drugbank.com/drugs/DB13931ApprovedInvestigationalsolution) 0.02% for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. … humour outflow to act as an inhibitor to the rho kinase and norepinephrine transporters found there as opposed to affecting protaglandin F2-alpha analog like mechanisms in the unconventional uveoscleral
Synonyms: (4-((1S)-1-(Aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4- dimethylbenzoate