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Allopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalIt was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942].
Synonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidineProducts: ALLOPURINOL 100 1A PHARMA, ALLOPURINOL 300 1A PHARMAAmisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalAmisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. … [A6752, L32764] Oral tablets of amisulpride is used in European countries as a treatment for acute and chronic schizophrenic disorders, as well as secondary negative symptoms in mental health disorders
Categories: Dopamine D2 Receptor AntagonistsProducts: AMISULPRIDE MYLAN GENERICSUstekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigational[A187346] The therapeutic use of the drug started in Canada, the US, and Europe since 2009 when it was first approved for the treatment of adult patients with moderate to severe plaque psoriasis and … In October 2019, it was also approved by the FDA for use to manage moderately to severely active ulcerative colitis in adults.
Besilesomab
go.drugbank.com/drugs/DB13979Approved[FDA Label]. … Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the
Rucaparib
go.drugbank.com/drugs/DB12332ApprovedInvestigationalPARP is an enzyme that plays an essential role in DNA repair. … By targeting the genetically-mutated cancer cells that lack a DNA repair mechanism, rucaparib causes cancer cell death and reduces tumour growth.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexStannous chloride
go.drugbank.com/drugs/DB11056ApprovedStannous chloride is used as a source of tin in radiopharmaceutical kits. … Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities [A32700].
Pramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic.
Mixtures: Dr Bells Pomade, Pomada De La Campana Triple Antibiotic Pain ReliefFluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnFluticasone is a synthetic glucocorticoid available as 2 esters, [DB08906] and [DB00588][F4355,F4358,F4361,F4364][FDA Label]. … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358,F4361,F4364][FDA Label].
Benazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: BENAZEPRIL 1A COM 20/25MG, BENAZEPRIL 1A COM10/12.5MGProducts: BENAZEPRIL 1A PHARMA 5MG, BENAZEPRIL 1A PHARMA 10MGFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … undergoing abdominal surgery who are are at high risk of thromboembolic complications; in the treatment of deep vein thrombosis (DVT) and pumonary embolism (PE); in the management of unstable angina (UA
Categories: Factor Xa Inhibitors, Indirect factor Xa inhibitors