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Displaying results 971 - 980 of 10000 in total
  1. Drug

    Lofexidine

    go.drugbank.com/drugs/DB04948
    ApprovedInvestigational

    Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.

    Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders
  2. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. … While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products.

    Mixtures: Re-action E, Nail Care Pen
  3. Drug

    Coagulation factor VII human

    go.drugbank.com/drugs/DB13150
    ApprovedInvestigational

    Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.

    Mixtures: Beriplex P/n 500, Beriplex P/n 1000Categories: coagulation factor IX, II, VII and X in combination
  4. Drug

    Aspergillus flavus

    go.drugbank.com/drugs/DB10694
    Approved

    Aspergillus flavus extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  5. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety of _in vivo_ and _in vitro_ models [A27218].

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Serplulimab

    go.drugbank.com/drugs/DB17451
    ApprovedInvestigational

    Most recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953] … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.

  7. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. … It can be used in severe cases of croup [L4824].

    International brands: Epi EZ Pen JRMixtures: Marcaine E, Marcaine E
  8. Drug

    Penicillium camemberti

    go.drugbank.com/drugs/DB10809
    Approved

    Penicillium camemberti extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  9. Drug

    Penicillium roqueforti

    go.drugbank.com/drugs/DB10812
    Approved

    Penicillium roqueforti extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  10. Drug

    Gluconic Acid

    go.drugbank.com/drugs/DB13180
    ApprovedInvestigational

    Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.

    Mixtures: Isolyte S in Dextrose, Plasmalyte 148 In Water