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Displaying results 981 - 990 of 10000 in total
  1. Drug

    AP1081

    go.drugbank.com/drugs/DB05233
    Experimental

    A transdermal gel containing ethinyl estradiol and norelgestromin being investigated by Antares Pharma for use as a female contraceptive.

  2. Drug

    Ecamsule

    go.drugbank.com/drugs/DB09534
    Approved

    Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only in a few products manufactured by L'Oreal. … Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability.

    Mixtures: Anthelios XL Melt-IN Cream, Kiehls Ultra Light Daily Uv Defense Tone Up SPF 50 Anti Pollution Instantly Brightens and HydratesCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Histrelin

    go.drugbank.com/drugs/DB06788
    ApprovedInvestigationalWithdrawn

    Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. … As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by the FDA in May 2007).[L41700]

    Synonyms: [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormoneCategories: Gonadotropin Releasing Hormone Receptor Agonist, Gonadotropin Releasing Hormone Receptor Agonists
  4. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904] … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.

    Categories: Serotonin Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsProducts: Propranolol Hydrochloride Injection USP
  5. Drug

    Enapotamab vedotin

    go.drugbank.com/drugs/DB16156
    Investigational

    Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).

    Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotin
  6. Drug

    Methionine

    go.drugbank.com/drugs/DB00134
    ApprovedInvestigationalNutraceutical

    A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  7. Drug

    Sulbutiamine

    go.drugbank.com/drugs/DB13416
    Investigational

    It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives. … Although its clinical efficacy is not yet defined, sulbutiamine is used to treat asthenia.

    Products: NEURO UP® TABLETAS CUBIERTA CON PELICULA 200 MG
  8. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys, the nerves, the heart, and other … [L47036,L47057,L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and an estimated more than 50 percent of these diagnosed patients are currently untreated

  9. Drug

    Seladelpar

    go.drugbank.com/drugs/DB12390
    ApprovedInvestigational

    Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. Seladelpar is a single enantiomer of the R-configuration. … [L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a condition associated with aberrant bile acid metabolism

    Synonyms: (4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)SULFANYL)-2-METHYLPHENOXY)ACETIC ACID PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) AGONIST,ANTIHYPERLIPIDAEMIC
  10. Drug

    Eucalyptus oil

    go.drugbank.com/drugs/DB11114
    Approved

    It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. … Eucalyptus oil can be applied directly to the skin for pain and swelling of respiratory tract mucous membranes, joint pain, genital herpes, and nasal stuffiness.

    Mixtures: Kaz Inhalant, K-LIDEX