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Displaying results 981 - 990 of 2482 in total
  1. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum anti...

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: CLOMACIN-P
  2. Drug

    Dicoumarol

    go.drugbank.com/drugs/DB00266
    Approved

    Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  3. Drug

    Isradipine

    go.drugbank.com/drugs/DB00270
    Approved

    Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blo...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Disopyramide

    go.drugbank.com/drugs/DB00280
    ApprovedInvestigational

    A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also po...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Ropivacaine

    go.drugbank.com/drugs/DB00296
    ApprovedInvestigational

    Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  6. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    Filapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  7. Drug

    Azamulin

    go.drugbank.com/drugs/DB20304
    Experimental

    Azamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  8. Drug

    Burapitant

    go.drugbank.com/drugs/DB20607
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Burapitant is a neurokinin NK1​ (substance P) receptor antagonist. Burapitant has a monoisotopic molecular weight of 681.2 Da.

  9. Drug

    Risperidone

    go.drugbank.com/drugs/DB00734
    ApprovedInvestigational

    Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, ...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  10. Drug

    Meclizine

    go.drugbank.com/drugs/DB00737
    ApprovedInvestigational

    Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholine...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates