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Midodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalIt is used as a vasoconstrictor agent in the treatment of hypotension.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AgonistsSynonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamideTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamideMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalMoxifloxacin is a synthetic fluoroquinolone antibiotic agent.
Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingNelfinavir
go.drugbank.com/drugs/DB00220ApprovedInvestigationalNelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsIsoetharine
go.drugbank.com/drugs/DB00221ApprovedIsoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.[A330]
Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigational2 diabetes mellitus. … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular
Mixtures: AMARYL®M 1 MG/ 500 MG, AMARYL®M 4 MG/ 1000 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesDiflorasone
go.drugbank.com/drugs/DB00223ApprovedDiflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
International brands: Florone EProducts: Psorcon E, ApexiCon EEnflurane
go.drugbank.com/drugs/DB00228ApprovedVet approvedWithdrawnEnflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesSynonyms: 2-chloro-1,1,2-trifluoroethyl difluoromethyl etherMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalHeart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through chemical modification of [amrinone].
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 InhibitorsSynonyms: 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrileAlclometasone
go.drugbank.com/drugs/DB00240ApprovedAlclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (7alpha,11beta,16alpha)-7-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione