Search

Displaying results 9911 - 9920 of 10000 in total
  1. Drug

    VAD-044

    go.drugbank.com/drugs/DB17697
    Investigational

    VAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098]

    Synonyms: 6-(4-((1S,3S)-1-amino-3-hydroxycyclobutyl)phenyl)-1-ethyl-7-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
  2. Drug

    8-azaguanine

    go.drugbank.com/drugs/DB01667
    Experimental

    8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 8 AG, Azaguanine-8
  3. Drug

    Muplestim

    go.drugbank.com/drugs/DB12431
    Investigational

    -3) in HIV Infected Patients With Cytopenia). … Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL

    Categories: Interleukin-3Synonyms: IL-3 (NON-GLYCOSYLATED), Interleukin 3
  4. Drug

    Azemiglitazone

    go.drugbank.com/drugs/DB16028
    Investigational

    of Three Dose Levels of MSDC-0602 in Type 2 Diabetic Patients). … Azemiglitazone is under investigation in clinical trial NCT01280695 (A Randomized, Double-blind, Comparator- and Placebo-controlled, Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Amlitelimab

    go.drugbank.com/drugs/DB18835
    Investigational

    Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years … and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).

    Synonyms: Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa.-chain, dimer
  6. Drug

    Insulin efsitora alfa

    go.drugbank.com/drugs/DB19013
    Investigational

    Insulin efsitora alfa is under investigation in clinical trial NCT05662332 (A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting … Basal Insulin for the First Time (QWINT-1)).

  7. Drug

    UDP-alpha-D-glucuronic acid

    go.drugbank.com/drugs/DB03041
    Experimental

    It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. … A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: UDP-D-glucuronate, UDP-alpha-D-glucuronate
  8. Drug

    PAS-004

    go.drugbank.com/drugs/DB18611
    Investigational

    PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.

  9. Drug

    Anti-CD7 CAR-T

    go.drugbank.com/drugs/DB23322
    Investigational

    CD7 CAR-T is a biologic drug. CD7 CAR-T is under investigation in clinical trial NCT07117305 (CD7 CAR-T Combined With Autologous Hematopoietic Stem Cell Transplantation).

    Synonyms: CD7 CAR T, CD7 CAR-T
  10. Drug

    Foliglurax

    go.drugbank.com/drugs/DB15292
    Investigational

    Foliglurax is under investigation in clinical trial NCT02639221 (A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic … Study in Healthy Male and Female Subjects).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring