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Displaying results 1 - 10 of 367 in total
  1. Target

    Aluminum

    go.drugbank.com/bio_entities/BE0004818
    TargetHumans

  2. Target

    sulfate adenylyltransferase

    go.drugbank.com/bio_entities/BE0003166
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    Polypeptides: sulfate adenylyltransferaseSynonyms: Sulfate adenylyltransferase, Sulfate adenylate transferase
  3. Target

    Dermatan sulfate

    go.drugbank.com/bio_entities/BE0004819
    TargetHumans

  4. Target

    Heparan sulfate

    go.drugbank.com/bio_entities/BE0004820
    TargetHumans

  5. Target

    Calcium and integrin-binding protein 1

    go.drugbank.com/bio_entities/BE0008691
    TargetHumans

    Down-regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling. … Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac

    Polypeptides: Calcium and integrin-binding protein 1Synonyms: Calcium- and integrin-binding protein
  6. Target

    Chondroitin sulfate proteoglycan 4

    go.drugbank.com/bio_entities/BE0015621
    TargetHumans

    May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. … May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades

    Polypeptides: Chondroitin sulfate proteoglycan 4Synonyms: Chondroitin sulfate proteoglycan NG2, Melanoma chondroitin sulfate proteoglycan
  7. Target

    Calcium and integrin-binding family member 2

    go.drugbank.com/bio_entities/BE0008698
    TargetHumans

    Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity). … Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970, PubMed:26426422)

    Polypeptides: Calcium and integrin-binding family member 2Function: calcium ion binding
  8. Target

    Calcium ions

    go.drugbank.com/bio_entities/BE0004817
    TargetHumans

  9. Target

    Calcium release-activated calcium channel protein 1

    go.drugbank.com/bio_entities/BE0018211
    TargetHumans

    Activates NFATC2/NFAT1 and NFATC3/NFAT4-mediated transcriptional responses. … Assembles with ORAI2 and ORAI3 to form hexameric CRAC channels that mediate Ca(2+) influx upon depletion of endoplasmic reticulum Ca(2+) store and channel activation by Ca(2+) sensor STIM1, a process known

    Polypeptides: Calcium release-activated calcium channel protein 1Function: calcium channel activity
  10. Target

    Calcium transporting ATPases

    go.drugbank.com/bio_entities/BE0010002
    TargetHumans

    Plays dual roles in osteoclast differentiation and survival by regulating RANKL-induced calcium oscillations in preosteoclasts and mediating calcium extrusion in mature osteoclasts (By similarity). … Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (PubMed:8530416).

    Polypeptides: Calcium-transporting ATPase type 2C member 1, Calcium-transporting ATPase type 2C member 2Synonyms: Calcium pump 1, Calcium pump 2