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DrugBest match

Canagliflozin

go.drugbank.com/drugs/DB08907
ApprovedInvestigational

Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label]. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 ...

  1. Indication

    Major Adverse Cardiac Events

    go.drugbank.com/conditions/DBCOND0061772
    Drugs: Canagliflozin
  2. Indication

    Doubling of serum creatinine

    go.drugbank.com/conditions/DBCOND0123104
    Drugs: Canagliflozin
  3. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...

    Mixtures: Vokanamet (Canagliflozin 150mg/ Metformin 500mg) Film-Coated Tablet, Vokanamet (Canagliflozin 150mg/ Metformin 850mg) Film-Coated TabletCategories: metformin and canagliflozin
  4. Indication

    End Stage Renal Disease (ESRD)

    go.drugbank.com/conditions/DBCOND0035540
    Drugs: Canagliflozin · Dapagliflozin · Empagliflozin · Finerenone · Metformin · Semaglutide
  5. Drug

    Empagliflozin

    go.drugbank.com/drugs/DB09038
    ApprovedInvestigational

    The development of C-glucoside phlorizin analogs remedied the issues observed in the previous generation, and led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin

  6. Drug

    Sotagliflozin

    go.drugbank.com/drugs/DB12713
    ApprovedInvestigational

    [L39705] Its potency in inhibiting SGLT2 is similar to that of other SGLT2 inhibitors, such as [canagliflozin] and [dapagliflozin], but its potency in inhibiting SGLT1 is >10-fold higher than its predecessors

  7. Indication

    Cardiovascular Mortality

    go.drugbank.com/conditions/DBCOND0040959
    Drugs: Acetylsalicylic acid · Canagliflozin · Colchicine · Dapagliflozin · Empagliflozin · Evolocumab +12 more
  8. Indication

    Type 2 Diabetes

    go.drugbank.com/conditions/DBCOND0030616
    Drugs: Acarbose · Albiglutide · Alogliptin · Bexagliflozin · Bromocriptine · Canagliflozin +40 more
  9. Pathway

    1,1-Dimethylbiguanide Drug Metabolism Pathway

    smpdb.ca/view/SMP0145440
    Metabolic

    Gadoversetamide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Gadoversetamide passes through the liver and is then excreted from the body mainly through the kidney.

    Drugs: Metformin