Search

Displaying all 4 results
DrugBest match

Emicizumab

go.drugbank.com/drugs/DB13923
ApprovedInvestigational

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstabl...

  1. Pathway

    Emicizumab Action Pathway

    smpdb.ca/view/SMP0126843
    Drug action

    Emicizumab performs the function of coagulation factor VIII, with the ability to also bind to both coagulation factor IX and X. … Emicizumab also known as Hemlibra, is a humanized recombinant monoclonal antibody that mimics coagulation factor VIII and can bind to activated coagulation factor IX and X.

    Drugs: Calcium · Emicizumab
  2. Drug

    Valoctocogene roxaparvovec

    go.drugbank.com/drugs/DB15561
    ApprovedInvestigationalWithdrawn

    [L43292] Hemophilia A treatments such as prophylactic regimens of exogenous factor VIII or [emicizumab] improve the clinical outcomes of patients but do not eliminate breakthrough bleeding.

  3. Indication

    Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089512
    Drugs: Anti-inhibitor coagulant complex · Coagulation factor VIIa Recombinant Human · Emicizumab · Fitusiran · Moroctocog alfa · Rurioctocog alfa pegol +2 more