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Urea transporter 2
go.drugbank.com/bio_entities/BE0004691TransporterHumansMediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism
Polypeptides: Urea transporter 2Synonyms: Urea transporter, kidneyUrea transporter 1
go.drugbank.com/bio_entities/BE0004692TransporterHumansMediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:10514515, PubMed:7797558, PubMed:7989337, PubMed:8997401). … Also mediates the transport of urea across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).
Polypeptides: Urea transporter 1Synonyms: Urea transporter, erythrocyteInterleukin-13
go.drugbank.com/bio_entities/BE0002438TargetHumansStimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (PubMed:7903680, PubMed:8759755). … Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (PubMed:21622864).
Polypeptides: Interleukin-13Synonyms: IL-13A disintegrin and metalloproteinase with thrombospondin motifs 13
go.drugbank.com/bio_entities/BE0009336EnzymeTargetHumansCleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 13Synonyms: ADAMTS-13, ADAM-TS 13Kelch protein 13
go.drugbank.com/bio_entities/BE0010314TargetPlasmodium falciparumPolypeptides: Kelch protein 13Retinol dehydrogenase 13
go.drugbank.com/bio_entities/BE0000593TargetHumansRetinol dehydrogenase with a clear preference for NADP. Oxidizes all-trans-retinol, but seems to reduce all-trans-retinal with much higher efficiency (PubMed:18039331). Has no activity toward steroids (PubMed:18039331)
Polypeptides: Retinol dehydrogenase 13Troponin C, slow skeletal and cardiac muscles
go.drugbank.com/bio_entities/BE0001024TargetHumansTn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. … The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments
Polypeptides: Troponin C, slow skeletal and cardiac musclesSynonyms: TN-CCarbonic anhydrase 13
go.drugbank.com/bio_entities/BE0003633TargetHumansCatalyzes the reversible conversion of carbon dioxide to hydrogencarbonate/bicarbonate and thus is essential in the regulation of pH and metabolic processes
Polypeptides: Carbonic anhydrase 13Cytochrome c3, 13 kDa
go.drugbank.com/bio_entities/BE0003056TargetDesulfovibrio baculatus (strain Norway 4)Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
Polypeptides: Cytochrome c3, 13 kDaC-C motif chemokine 5
go.drugbank.com/bio_entities/BE0000975TargetHumansChemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. … May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation.
Polypeptides: C-C motif chemokine 5