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Ecto-NOX disulfide-thiol exchanger 2
go.drugbank.com/bio_entities/BE0002434TargetHumansProbably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. … Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement
Synonyms: Tumor-associated hydroquinone oxidaseRibosyldihydronicotinamide dehydrogenase [quinone]
go.drugbank.com/bio_entities/BE0000220TargetEnzymeHumansThe enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin
Ferroptosis suppressor protein 1
go.drugbank.com/bio_entities/BE0018843TargetEnzymeHumansHydroquinones act as potent radical-trapping antioxidants inhibitor of phospholipid peroxidation and ferroptosis (PubMed:35922516). … antioxidant by mediating warfarin-resistant vitamin K reduction in the canonical vitamin K cycle: catalyzes NAD(P)H-dependent reduction of vitamin K (phylloquinone, menaquinone-4 and menadione) to hydroquinone
Cytochrome b6-f complex iron-sulfur subunit
go.drugbank.com/bio_entities/BE0002474TargetMastigocladus laminosusComponent of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Vitamin K-dependent gamma-carboxylase
go.drugbank.com/bio_entities/BE0000403TargetHumansMediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant epoxidation of vitamin K hydroquinone to vitamin K epoxide
NAD(P)H dehydrogenase [quinone] 1
go.drugbank.com/bio_entities/BE0001184TargetEnzymeHumansReduces components of plasma membrane redox system such as coenzyme Q and vitamin quinones, producing antioxidant hydroquinone forms. … Flavin-containing quinone reductase that catalyzes two-electron reduction of quinones to hydroquinones using either NADH or NADPH as electron donors.